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        <description>THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.</description>
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                <title>The Big Unlock</title>
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                <itunes:subtitle>THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.</itunes:subtitle>
        <itunes:author>Rohit Mahajan &amp; Ritu M. Uberoy</itunes:author>
        <itunes:type>episodic</itunes:type>
        <itunes:summary>THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.</itunes:summary>
        <itunes:owner>
            <itunes:name>Rohit Mahajan</itunes:name>
            <itunes:email>info@damoconsulting.net</itunes:email>
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                <title>
                    <![CDATA[Accelerating Pediatric Digital Health Innovation Through Deep Institutional Collaboration]]>
                </title>
                <pubDate>Tue, 09 Jun 2026 08:32:21 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
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                    https://permalink.castos.com/podcast/5282/episode/2476987</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/accelerating-pediatric-digital-health-innovation-through-deep-institutional-collaboration</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Omkar Kulkarni, VP, Chief Transformation &amp; Innovation Officer, Children's Hospital Los Angeles (CHLA)" href="https://soundcloud.com/thebigunlock/omkar-kulkarni-vp-chief" target="_blank" rel="noreferrer noopener">Omkar Kulkarni, VP, Chief Transformation &amp; Innovation Officer, Children’s Hospital Los Angeles (CHLA)</a>
<p>In this episode, Omkar Kulkarni, VP, Chief Transformation &amp; Innovation Officer at Children’s Hospital Los Angeles (CHLA), outlines the stark funding gap in pediatric innovation, which receives less than 1% of digital health investments despite children making up 20% of the population. To combat this, the CHLA-led KidsX consortium unites children’s hospitals nationwide to scale early-stage digital solutions through collaboration over competition.</p>
<p>Omkar suggests that pediatrics requires entirely separate technological blueprints, hence digital tools must be designed for adult caregivers, accommodate strict adolescent privacy laws at age 12, and scale across diverse physiological sizes. He highlights vital innovation pipelines, including AI tools targeting the youth mental health crisis, longitudinal chronic care management, and 24/7 validated conversational interfaces for parents.</p>
<p>For healthcare startups entering this space, Omkar emphasizes that the key to building institutional trust relies on presenting deep, heterogeneous clinical evidence, establishing commercially viable billing frameworks, and practicing deep humility when approaching complex clinical partnerships. He believes that generative AI will not replace clinicians but will instead automate administrative tasks, empowering them to focus on top-of-license, human-to-human care. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Omkar Kulkarni, VP, Chief Transformation & Innovation Officer, Children’s Hospital Los Angeles (CHLA)
In this episode, Omkar Kulkarni, VP, Chief Transformation & Innovation Officer at Children’s Hospital Los Angeles (CHLA), outlines the stark funding gap in pediatric innovation, which receives less than 1% of digital health investments despite children making up 20% of the population. To combat this, the CHLA-led KidsX consortium unites children’s hospitals nationwide to scale early-stage digital solutions through collaboration over competition.
Omkar suggests that pediatrics requires entirely separate technological blueprints, hence digital tools must be designed for adult caregivers, accommodate strict adolescent privacy laws at age 12, and scale across diverse physiological sizes. He highlights vital innovation pipelines, including AI tools targeting the youth mental health crisis, longitudinal chronic care management, and 24/7 validated conversational interfaces for parents.
For healthcare startups entering this space, Omkar emphasizes that the key to building institutional trust relies on presenting deep, heterogeneous clinical evidence, establishing commercially viable billing frameworks, and practicing deep humility when approaching complex clinical partnerships. He believes that generative AI will not replace clinicians but will instead automate administrative tasks, empowering them to focus on top-of-license, human-to-human care. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Accelerating Pediatric Digital Health Innovation Through Deep Institutional Collaboration]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
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                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Omkar Kulkarni, VP, Chief Transformation &amp; Innovation Officer, Children's Hospital Los Angeles (CHLA)" href="https://soundcloud.com/thebigunlock/omkar-kulkarni-vp-chief" target="_blank" rel="noreferrer noopener">Omkar Kulkarni, VP, Chief Transformation &amp; Innovation Officer, Children’s Hospital Los Angeles (CHLA)</a>
<p>In this episode, Omkar Kulkarni, VP, Chief Transformation &amp; Innovation Officer at Children’s Hospital Los Angeles (CHLA), outlines the stark funding gap in pediatric innovation, which receives less than 1% of digital health investments despite children making up 20% of the population. To combat this, the CHLA-led KidsX consortium unites children’s hospitals nationwide to scale early-stage digital solutions through collaboration over competition.</p>
<p>Omkar suggests that pediatrics requires entirely separate technological blueprints, hence digital tools must be designed for adult caregivers, accommodate strict adolescent privacy laws at age 12, and scale across diverse physiological sizes. He highlights vital innovation pipelines, including AI tools targeting the youth mental health crisis, longitudinal chronic care management, and 24/7 validated conversational interfaces for parents.</p>
<p>For healthcare startups entering this space, Omkar emphasizes that the key to building institutional trust relies on presenting deep, heterogeneous clinical evidence, establishing commercially viable billing frameworks, and practicing deep humility when approaching complex clinical partnerships. He believes that generative AI will not replace clinicians but will instead automate administrative tasks, empowering them to focus on top-of-license, human-to-human care. Take a listen.</p>]]>
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                                <itunes:summary>
                    <![CDATA[The Big Unlock · Omkar Kulkarni, VP, Chief Transformation & Innovation Officer, Children’s Hospital Los Angeles (CHLA)
In this episode, Omkar Kulkarni, VP, Chief Transformation & Innovation Officer at Children’s Hospital Los Angeles (CHLA), outlines the stark funding gap in pediatric innovation, which receives less than 1% of digital health investments despite children making up 20% of the population. To combat this, the CHLA-led KidsX consortium unites children’s hospitals nationwide to scale early-stage digital solutions through collaboration over competition.
Omkar suggests that pediatrics requires entirely separate technological blueprints, hence digital tools must be designed for adult caregivers, accommodate strict adolescent privacy laws at age 12, and scale across diverse physiological sizes. He highlights vital innovation pipelines, including AI tools targeting the youth mental health crisis, longitudinal chronic care management, and 24/7 validated conversational interfaces for parents.
For healthcare startups entering this space, Omkar emphasizes that the key to building institutional trust relies on presenting deep, heterogeneous clinical evidence, establishing commercially viable billing frameworks, and practicing deep humility when approaching complex clinical partnerships. He believes that generative AI will not replace clinicians but will instead automate administrative tasks, empowering them to focus on top-of-license, human-to-human care. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2476987/c1a-gd22-rkg9d1k0cnqw-6f6ysp.png"></itunes:image>
                                                                            <itunes:duration>00:25:38</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Restoring the Intimate Physician Patient Relationship with Ambient AI]]>
                </title>
                <pubDate>Tue, 02 Jun 2026 10:26:28 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2472151</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/restoring-the-intimate-physician-patient-relationship-with-ambient-ai</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth" href="https://soundcloud.com/thebigunlock/podcast-with-dr-nele-jessel" target="_blank" rel="noreferrer noopener">Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth</a>
<p>In this episode, Dr. Nele Jessel, Chief Medical Officer at athenahealth, explores the rapid shift in physician sentiment toward AI and why healthcare may finally be reaching a true inflection point in digital transformation. Dr. Jessel explains how decades of EHR-induced administrative burnout initially made clinicians wary of new technology. However, the arrival of ambient note generation changed the game almost overnight, removing immense cognitive load and restoring the intimate, face-to-face physician-patient relationship.</p>
<p>A core theme of the discussion is the critical pivot toward clinician-guided development rather than vendor-driven solutions. Dr. Jessel details how athenahealth uses rapid “pre-alpha” prototyping to tackle the modern challenge of interoperability data-overload, deploying large language models to synthesize complex clinical records into actionable insights at the point of care. While emphasizing that medicine remains an art that requires a human in the loop for diagnostics, she outlines a future where autonomous, agentic AI conquers administrative burdens like prior authorizations. Ultimately, healthcare is reaching a true inflection point, transforming the EHR from a passive data repository into an invisible, intelligent assistant. Take a listen.</p>
<p><strong><em>This guest appearance was facilitated through conversations initiated at </em></strong><a href="https://hlth.com/about-us"><strong><em>ViVE</em></strong></a><strong><em>.</em></strong></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth
In this episode, Dr. Nele Jessel, Chief Medical Officer at athenahealth, explores the rapid shift in physician sentiment toward AI and why healthcare may finally be reaching a true inflection point in digital transformation. Dr. Jessel explains how decades of EHR-induced administrative burnout initially made clinicians wary of new technology. However, the arrival of ambient note generation changed the game almost overnight, removing immense cognitive load and restoring the intimate, face-to-face physician-patient relationship.
A core theme of the discussion is the critical pivot toward clinician-guided development rather than vendor-driven solutions. Dr. Jessel details how athenahealth uses rapid “pre-alpha” prototyping to tackle the modern challenge of interoperability data-overload, deploying large language models to synthesize complex clinical records into actionable insights at the point of care. While emphasizing that medicine remains an art that requires a human in the loop for diagnostics, she outlines a future where autonomous, agentic AI conquers administrative burdens like prior authorizations. Ultimately, healthcare is reaching a true inflection point, transforming the EHR from a passive data repository into an invisible, intelligent assistant. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Restoring the Intimate Physician Patient Relationship with Ambient AI]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth" href="https://soundcloud.com/thebigunlock/podcast-with-dr-nele-jessel" target="_blank" rel="noreferrer noopener">Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth</a>
<p>In this episode, Dr. Nele Jessel, Chief Medical Officer at athenahealth, explores the rapid shift in physician sentiment toward AI and why healthcare may finally be reaching a true inflection point in digital transformation. Dr. Jessel explains how decades of EHR-induced administrative burnout initially made clinicians wary of new technology. However, the arrival of ambient note generation changed the game almost overnight, removing immense cognitive load and restoring the intimate, face-to-face physician-patient relationship.</p>
<p>A core theme of the discussion is the critical pivot toward clinician-guided development rather than vendor-driven solutions. Dr. Jessel details how athenahealth uses rapid “pre-alpha” prototyping to tackle the modern challenge of interoperability data-overload, deploying large language models to synthesize complex clinical records into actionable insights at the point of care. While emphasizing that medicine remains an art that requires a human in the loop for diagnostics, she outlines a future where autonomous, agentic AI conquers administrative burdens like prior authorizations. Ultimately, healthcare is reaching a true inflection point, transforming the EHR from a passive data repository into an invisible, intelligent assistant. Take a listen.</p>
<p><strong><em>This guest appearance was facilitated through conversations initiated at </em></strong><a href="https://hlth.com/about-us"><strong><em>ViVE</em></strong></a><strong><em>.</em></strong></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2472151/c1e-gd22br0z8ru24j16-kpo3p7z8iw22-f1vts2.mp3" length="24568389"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth
In this episode, Dr. Nele Jessel, Chief Medical Officer at athenahealth, explores the rapid shift in physician sentiment toward AI and why healthcare may finally be reaching a true inflection point in digital transformation. Dr. Jessel explains how decades of EHR-induced administrative burnout initially made clinicians wary of new technology. However, the arrival of ambient note generation changed the game almost overnight, removing immense cognitive load and restoring the intimate, face-to-face physician-patient relationship.
A core theme of the discussion is the critical pivot toward clinician-guided development rather than vendor-driven solutions. Dr. Jessel details how athenahealth uses rapid “pre-alpha” prototyping to tackle the modern challenge of interoperability data-overload, deploying large language models to synthesize complex clinical records into actionable insights at the point of care. While emphasizing that medicine remains an art that requires a human in the loop for diagnostics, she outlines a future where autonomous, agentic AI conquers administrative burdens like prior authorizations. Ultimately, healthcare is reaching a true inflection point, transforming the EHR from a passive data repository into an invisible, intelligent assistant. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2472151/c1a-gd22-474womo4sxm6-t2ip96.png"></itunes:image>
                                                                            <itunes:duration>00:25:36</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Pilot Purgatory to Enterprise Impact and the Unicorn Protocol for AI Success]]>
                </title>
                <pubDate>Tue, 26 May 2026 09:01:01 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2463401</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/pilot-purgatory-to-enterprise-impact-and-the-unicorn-protocol-for-ai-success</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Sally Ann Frank, Global Lead – Health &amp; Life Sciences, Microsoft for Startups" href="https://soundcloud.com/thebigunlock/sally-ann-frank-global-lead" target="_blank" rel="noreferrer noopener">Sally Ann Frank, Global Lead – Health &amp; Life Sciences, Microsoft for Startups</a>
<p>In this episode, Sally Ann Frank, Global Lead for Health and Life Sciences at Microsoft for Startups, discusses how AI is moving beyond experimentation toward measurable enterprise impact. She emphasizes that the most successful startups differentiate themselves not just through technology innovation, but through evolving business models, strong customer discovery practices, and a coachable mindset grounded in strategic mentorship.</p>
<p>Sally explores the challenge of “pilot purgatory,” noting that founders must design for production from day one. Establishing clear ROI frameworks and demonstrating early value are essential to maintaining momentum and avoiding the law of diminishing interest often seen in stalled pilots. Looking toward 2026, Sally envisions a “show me the money” era centered on four bridges: expanding global access through virtual technology to democratize care, closing the investment gap in women’s health beyond reproductive care, advancing AI-driven precision medicine through genetics for individualized treatment, and shifting healthcare from reactive treatment toward preventative longevity. Ultimately, the conversation highlights that lasting success in AI will belong to organizations that evolve into trusted advisors, consistently delivering value at every interaction. Take a listen.</p>
<p><strong><em>This guest appearance was facilitated through conversations initiated at </em></strong><a href="https://www.himss.org/who-we-are/"><strong><em>HIMSS</em></strong></a><strong><em>.</em></strong></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Sally Ann Frank, Global Lead – Health & Life Sciences, Microsoft for Startups
In this episode, Sally Ann Frank, Global Lead for Health and Life Sciences at Microsoft for Startups, discusses how AI is moving beyond experimentation toward measurable enterprise impact. She emphasizes that the most successful startups differentiate themselves not just through technology innovation, but through evolving business models, strong customer discovery practices, and a coachable mindset grounded in strategic mentorship.
Sally explores the challenge of “pilot purgatory,” noting that founders must design for production from day one. Establishing clear ROI frameworks and demonstrating early value are essential to maintaining momentum and avoiding the law of diminishing interest often seen in stalled pilots. Looking toward 2026, Sally envisions a “show me the money” era centered on four bridges: expanding global access through virtual technology to democratize care, closing the investment gap in women’s health beyond reproductive care, advancing AI-driven precision medicine through genetics for individualized treatment, and shifting healthcare from reactive treatment toward preventative longevity. Ultimately, the conversation highlights that lasting success in AI will belong to organizations that evolve into trusted advisors, consistently delivering value at every interaction. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Pilot Purgatory to Enterprise Impact and the Unicorn Protocol for AI Success]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Sally Ann Frank, Global Lead – Health &amp; Life Sciences, Microsoft for Startups" href="https://soundcloud.com/thebigunlock/sally-ann-frank-global-lead" target="_blank" rel="noreferrer noopener">Sally Ann Frank, Global Lead – Health &amp; Life Sciences, Microsoft for Startups</a>
<p>In this episode, Sally Ann Frank, Global Lead for Health and Life Sciences at Microsoft for Startups, discusses how AI is moving beyond experimentation toward measurable enterprise impact. She emphasizes that the most successful startups differentiate themselves not just through technology innovation, but through evolving business models, strong customer discovery practices, and a coachable mindset grounded in strategic mentorship.</p>
<p>Sally explores the challenge of “pilot purgatory,” noting that founders must design for production from day one. Establishing clear ROI frameworks and demonstrating early value are essential to maintaining momentum and avoiding the law of diminishing interest often seen in stalled pilots. Looking toward 2026, Sally envisions a “show me the money” era centered on four bridges: expanding global access through virtual technology to democratize care, closing the investment gap in women’s health beyond reproductive care, advancing AI-driven precision medicine through genetics for individualized treatment, and shifting healthcare from reactive treatment toward preventative longevity. Ultimately, the conversation highlights that lasting success in AI will belong to organizations that evolve into trusted advisors, consistently delivering value at every interaction. Take a listen.</p>
<p><strong><em>This guest appearance was facilitated through conversations initiated at </em></strong><a href="https://www.himss.org/who-we-are/"><strong><em>HIMSS</em></strong></a><strong><em>.</em></strong></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2463401/c1e-k522cdv4kks945m7-xxkx0qkwb7p2-jacwp1.mp3" length="20992614"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Sally Ann Frank, Global Lead – Health & Life Sciences, Microsoft for Startups
In this episode, Sally Ann Frank, Global Lead for Health and Life Sciences at Microsoft for Startups, discusses how AI is moving beyond experimentation toward measurable enterprise impact. She emphasizes that the most successful startups differentiate themselves not just through technology innovation, but through evolving business models, strong customer discovery practices, and a coachable mindset grounded in strategic mentorship.
Sally explores the challenge of “pilot purgatory,” noting that founders must design for production from day one. Establishing clear ROI frameworks and demonstrating early value are essential to maintaining momentum and avoiding the law of diminishing interest often seen in stalled pilots. Looking toward 2026, Sally envisions a “show me the money” era centered on four bridges: expanding global access through virtual technology to democratize care, closing the investment gap in women’s health beyond reproductive care, advancing AI-driven precision medicine through genetics for individualized treatment, and shifting healthcare from reactive treatment toward preventative longevity. Ultimately, the conversation highlights that lasting success in AI will belong to organizations that evolve into trusted advisors, consistently delivering value at every interaction. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2463401/c1a-gd22-qdp20wx3t4n0-4mvpcl.png"></itunes:image>
                                                                            <itunes:duration>00:21:53</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Rural Resilience and Balancing Clinical Care with AI Innovation]]>
                </title>
                <pubDate>Tue, 19 May 2026 07:37:38 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2459868</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/rural-resilience-and-balancing-clinical-care-with-ai-innovation</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Andrew Porter, CEO, Wayne General Hospital" href="https://soundcloud.com/thebigunlock/andrew-porter-ceo-wayne" target="_blank" rel="noreferrer noopener">Andrew Porter, CEO, Wayne General Hospital</a>


<p>In this episode, Andrew Porter, CEO of Wayne General Hospital, shares how a community-based health system is navigating the dual pressures of financial sustainability and rural healthcare delivery. Drawing on his unique “three-legged stool” perspective as a clinician, administrator, and academic, Andrew highlights the necessity of staying nimble in a rapidly evolving market.</p>
<p>Wayne General is taking a pragmatic approach to AI by focusing on real problems instead of technology hype. Andrew details the successful implementation of ambient AI documentation, which has improved provider satisfaction and restored the intimacy of the patient-physician relationship. He also discusses leveraging AI partnerships to bring high-sophistication care, such as heart murmur detection, to rural populations. Andrew emphasizes the critical need for AI-driven transformation in the revenue cycle to alleviate the administrative complexity burdening small hospitals. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Andrew Porter, CEO, Wayne General Hospital


In this episode, Andrew Porter, CEO of Wayne General Hospital, shares how a community-based health system is navigating the dual pressures of financial sustainability and rural healthcare delivery. Drawing on his unique “three-legged stool” perspective as a clinician, administrator, and academic, Andrew highlights the necessity of staying nimble in a rapidly evolving market.
Wayne General is taking a pragmatic approach to AI by focusing on real problems instead of technology hype. Andrew details the successful implementation of ambient AI documentation, which has improved provider satisfaction and restored the intimacy of the patient-physician relationship. He also discusses leveraging AI partnerships to bring high-sophistication care, such as heart murmur detection, to rural populations. Andrew emphasizes the critical need for AI-driven transformation in the revenue cycle to alleviate the administrative complexity burdening small hospitals. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Rural Resilience and Balancing Clinical Care with AI Innovation]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Andrew Porter, CEO, Wayne General Hospital" href="https://soundcloud.com/thebigunlock/andrew-porter-ceo-wayne" target="_blank" rel="noreferrer noopener">Andrew Porter, CEO, Wayne General Hospital</a>


<p>In this episode, Andrew Porter, CEO of Wayne General Hospital, shares how a community-based health system is navigating the dual pressures of financial sustainability and rural healthcare delivery. Drawing on his unique “three-legged stool” perspective as a clinician, administrator, and academic, Andrew highlights the necessity of staying nimble in a rapidly evolving market.</p>
<p>Wayne General is taking a pragmatic approach to AI by focusing on real problems instead of technology hype. Andrew details the successful implementation of ambient AI documentation, which has improved provider satisfaction and restored the intimacy of the patient-physician relationship. He also discusses leveraging AI partnerships to bring high-sophistication care, such as heart murmur detection, to rural populations. Andrew emphasizes the critical need for AI-driven transformation in the revenue cycle to alleviate the administrative complexity burdening small hospitals. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2459868/c1e-qxrru7k19ju0vkd3-8d8mn0rnfpoo-leixbm.mp3" length="19556049"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Andrew Porter, CEO, Wayne General Hospital


In this episode, Andrew Porter, CEO of Wayne General Hospital, shares how a community-based health system is navigating the dual pressures of financial sustainability and rural healthcare delivery. Drawing on his unique “three-legged stool” perspective as a clinician, administrator, and academic, Andrew highlights the necessity of staying nimble in a rapidly evolving market.
Wayne General is taking a pragmatic approach to AI by focusing on real problems instead of technology hype. Andrew details the successful implementation of ambient AI documentation, which has improved provider satisfaction and restored the intimacy of the patient-physician relationship. He also discusses leveraging AI partnerships to bring high-sophistication care, such as heart murmur detection, to rural populations. Andrew emphasizes the critical need for AI-driven transformation in the revenue cycle to alleviate the administrative complexity burdening small hospitals. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2459868/c1a-gd22-dmjv8k01i41p-kjkeam.png"></itunes:image>
                                                                            <itunes:duration>00:20:23</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Reimagining Healthcare Through AI-Native Orchestration and Digital Platforms]]>
                </title>
                <pubDate>Wed, 13 May 2026 06:45:35 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2454266</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/reimagining-healthcare-through-ai-native-orchestration-and-digital-platforms</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health" href="https://soundcloud.com/thebigunlock/bharat-sutariya-md-senior-vice" target="_blank" rel="noreferrer noopener">Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health</a>
<p>In this episode, Dr. Bharat Sutariya, Senior Vice President and Chief Health Officer at Oracle Health, discusses the radical transformation of healthcare through AI-native digital platforms. As an emergency physician with over 25 years of experience, including leadership roles at Cerner and Deloitte, Dr. Sutariya provides a unique perspective on moving past the “burden” of legacy EHR systems.</p>
<p>The core of the conversation centers on Oracle’s bold bet: moving away from the industry-standard “bolt-on” AI approach. Instead, Oracle is rebuilding the healthcare stack from the ground up, embedding AI into the foundational layer. Dr. Sutariya argues that the future of healthcare technology isn’t just about capturing data but about systems of orchestration. This means AI that doesn’t just transcribe a note but listens to the clinical intent to automatically queue orders, handle referrals, and initiate prior authorizations.</p>
<p>Dr. Sutariya predicts that within a year, the conversation will shift from documentation efficiency to a truly connected, intelligent ecosystem that gives time back to both providers and patients. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://www.himss.org/who-we-are/"><em>HIMSS</em></a><em>.</em></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health
In this episode, Dr. Bharat Sutariya, Senior Vice President and Chief Health Officer at Oracle Health, discusses the radical transformation of healthcare through AI-native digital platforms. As an emergency physician with over 25 years of experience, including leadership roles at Cerner and Deloitte, Dr. Sutariya provides a unique perspective on moving past the “burden” of legacy EHR systems.
The core of the conversation centers on Oracle’s bold bet: moving away from the industry-standard “bolt-on” AI approach. Instead, Oracle is rebuilding the healthcare stack from the ground up, embedding AI into the foundational layer. Dr. Sutariya argues that the future of healthcare technology isn’t just about capturing data but about systems of orchestration. This means AI that doesn’t just transcribe a note but listens to the clinical intent to automatically queue orders, handle referrals, and initiate prior authorizations.
Dr. Sutariya predicts that within a year, the conversation will shift from documentation efficiency to a truly connected, intelligent ecosystem that gives time back to both providers and patients. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Reimagining Healthcare Through AI-Native Orchestration and Digital Platforms]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health" href="https://soundcloud.com/thebigunlock/bharat-sutariya-md-senior-vice" target="_blank" rel="noreferrer noopener">Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health</a>
<p>In this episode, Dr. Bharat Sutariya, Senior Vice President and Chief Health Officer at Oracle Health, discusses the radical transformation of healthcare through AI-native digital platforms. As an emergency physician with over 25 years of experience, including leadership roles at Cerner and Deloitte, Dr. Sutariya provides a unique perspective on moving past the “burden” of legacy EHR systems.</p>
<p>The core of the conversation centers on Oracle’s bold bet: moving away from the industry-standard “bolt-on” AI approach. Instead, Oracle is rebuilding the healthcare stack from the ground up, embedding AI into the foundational layer. Dr. Sutariya argues that the future of healthcare technology isn’t just about capturing data but about systems of orchestration. This means AI that doesn’t just transcribe a note but listens to the clinical intent to automatically queue orders, handle referrals, and initiate prior authorizations.</p>
<p>Dr. Sutariya predicts that within a year, the conversation will shift from documentation efficiency to a truly connected, intelligent ecosystem that gives time back to both providers and patients. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://www.himss.org/who-we-are/"><em>HIMSS</em></a><em>.</em></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2454266/c1e-xmvvu1v6ndan7og5-345xzg78upp7-qst0ux.mp3" length="24648453"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health
In this episode, Dr. Bharat Sutariya, Senior Vice President and Chief Health Officer at Oracle Health, discusses the radical transformation of healthcare through AI-native digital platforms. As an emergency physician with over 25 years of experience, including leadership roles at Cerner and Deloitte, Dr. Sutariya provides a unique perspective on moving past the “burden” of legacy EHR systems.
The core of the conversation centers on Oracle’s bold bet: moving away from the industry-standard “bolt-on” AI approach. Instead, Oracle is rebuilding the healthcare stack from the ground up, embedding AI into the foundational layer. Dr. Sutariya argues that the future of healthcare technology isn’t just about capturing data but about systems of orchestration. This means AI that doesn’t just transcribe a note but listens to the clinical intent to automatically queue orders, handle referrals, and initiate prior authorizations.
Dr. Sutariya predicts that within a year, the conversation will shift from documentation efficiency to a truly connected, intelligent ecosystem that gives time back to both providers and patients. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2454266/c1a-gd22-pknk9wwjcznm-hslaoo.png"></itunes:image>
                                                                            <itunes:duration>00:25:41</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Building Strategy-Driven Technology in Rural Health Systems]]>
                </title>
                <pubDate>Tue, 05 May 2026 07:51:25 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2439853</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/building-strategy-driven-technology-in-rural-health-systems</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Linda Stevenson, Chief Operations &amp; Information Officer, Fisher-Titus Health" href="https://soundcloud.com/thebigunlock/linda-stevenson-chief" target="_blank" rel="noreferrer noopener">Linda Stevenson, Chief Operations &amp; Information Officer, Fisher-Titus Health</a>
<p>In this episode, Linda Stevenson, Chief Operations &amp; Information Officer at Fisher-Titus Health, shares how rural health systems are driving innovation under significant resource constraints. Leading a 100-bed community hospital with a lean IT team, she highlights the realities of “doing more with less”—from workforce shortages to the critical need for interoperability in coordinating care beyond organizational walls.</p>
<p>Linda challenges the industry’s fixation on AI as a standalone strategy, advocating instead for a problem-first approach: start with the clinical or operational need, then determine if AI is the right fit. She emphasizes that true transformation comes from aligning technology with enterprise priorities, not chasing hype.</p>
<p>She also points to persistent gaps in interoperability and growing cybersecurity risks, particularly in rural settings where vulnerabilities can impact the broader ecosystem. Her message is clear: stay grounded in strategy, focus on outcomes, and prioritize partnership over products to drive meaningful, scalable change. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://hlth.com/about-us"><strong><em>ViVE</em></strong></a><em>.</em></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Linda Stevenson, Chief Operations & Information Officer, Fisher-Titus Health
In this episode, Linda Stevenson, Chief Operations & Information Officer at Fisher-Titus Health, shares how rural health systems are driving innovation under significant resource constraints. Leading a 100-bed community hospital with a lean IT team, she highlights the realities of “doing more with less”—from workforce shortages to the critical need for interoperability in coordinating care beyond organizational walls.
Linda challenges the industry’s fixation on AI as a standalone strategy, advocating instead for a problem-first approach: start with the clinical or operational need, then determine if AI is the right fit. She emphasizes that true transformation comes from aligning technology with enterprise priorities, not chasing hype.
She also points to persistent gaps in interoperability and growing cybersecurity risks, particularly in rural settings where vulnerabilities can impact the broader ecosystem. Her message is clear: stay grounded in strategy, focus on outcomes, and prioritize partnership over products to drive meaningful, scalable change. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Building Strategy-Driven Technology in Rural Health Systems]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Linda Stevenson, Chief Operations &amp; Information Officer, Fisher-Titus Health" href="https://soundcloud.com/thebigunlock/linda-stevenson-chief" target="_blank" rel="noreferrer noopener">Linda Stevenson, Chief Operations &amp; Information Officer, Fisher-Titus Health</a>
<p>In this episode, Linda Stevenson, Chief Operations &amp; Information Officer at Fisher-Titus Health, shares how rural health systems are driving innovation under significant resource constraints. Leading a 100-bed community hospital with a lean IT team, she highlights the realities of “doing more with less”—from workforce shortages to the critical need for interoperability in coordinating care beyond organizational walls.</p>
<p>Linda challenges the industry’s fixation on AI as a standalone strategy, advocating instead for a problem-first approach: start with the clinical or operational need, then determine if AI is the right fit. She emphasizes that true transformation comes from aligning technology with enterprise priorities, not chasing hype.</p>
<p>She also points to persistent gaps in interoperability and growing cybersecurity risks, particularly in rural settings where vulnerabilities can impact the broader ecosystem. Her message is clear: stay grounded in strategy, focus on outcomes, and prioritize partnership over products to drive meaningful, scalable change. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://hlth.com/about-us"><strong><em>ViVE</em></strong></a><em>.</em></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2439853/c1e-njwwcz8vj7a9z21p-v6vp661xtp1-ykcywq.mp3" length="17879709"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Linda Stevenson, Chief Operations & Information Officer, Fisher-Titus Health
In this episode, Linda Stevenson, Chief Operations & Information Officer at Fisher-Titus Health, shares how rural health systems are driving innovation under significant resource constraints. Leading a 100-bed community hospital with a lean IT team, she highlights the realities of “doing more with less”—from workforce shortages to the critical need for interoperability in coordinating care beyond organizational walls.
Linda challenges the industry’s fixation on AI as a standalone strategy, advocating instead for a problem-first approach: start with the clinical or operational need, then determine if AI is the right fit. She emphasizes that true transformation comes from aligning technology with enterprise priorities, not chasing hype.
She also points to persistent gaps in interoperability and growing cybersecurity risks, particularly in rural settings where vulnerabilities can impact the broader ecosystem. Her message is clear: stay grounded in strategy, focus on outcomes, and prioritize partnership over products to drive meaningful, scalable change. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2439853/c1a-gd22-9jgwkmn9i50w-af4m5u.png"></itunes:image>
                                                                            <itunes:duration>00:18:38</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Adoption in Healthcare Must Be Led by Clinicians]]>
                </title>
                <pubDate>Thu, 30 Apr 2026 11:52:14 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2431411</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-adoption-in-healthcare-must-be-led-by-clinicians</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital" href="https://soundcloud.com/thebigunlock/dr-ruchi-garg-chief-medical" target="_blank" rel="noreferrer noopener">Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital</a>
<p>In this episode, Dr. Ruchi Garg, Chief Medical Officer at Fairview Park Hospital, shares how frontline clinicians are shaping the responsible adoption of AI in real-world care settings. Dr. Garg highlights how COVID accelerated digital adoption, from telehealth to remote patient monitoring, demonstrating that care can be both accessible and efficient when technology is thoughtfully applied.</p>
<p>Dr. Garg underscores that AI’s true value lies in reducing administrative burden, particularly in areas like documentation and prior authorization, where inefficiencies delay care and strain clinician-patient relationships. She notes that ambient AI is already improving accuracy and saving hours for physicians, with the next wave extending into orders, workflows, and care coordination.</p>
<p>However, she emphasizes that successful adoption depends on clinician involvement, intuitive design, and minimizing workflow friction. While AI may take on more clinical decision-making, questions around trust, liability, and human oversight remain central, making it critical for healthcare leaders to actively shape, not resist, this transformation. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at <a href="https://hlth.com/about-us"><strong>ViVE</strong></a>.</em></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital
In this episode, Dr. Ruchi Garg, Chief Medical Officer at Fairview Park Hospital, shares how frontline clinicians are shaping the responsible adoption of AI in real-world care settings. Dr. Garg highlights how COVID accelerated digital adoption, from telehealth to remote patient monitoring, demonstrating that care can be both accessible and efficient when technology is thoughtfully applied.
Dr. Garg underscores that AI’s true value lies in reducing administrative burden, particularly in areas like documentation and prior authorization, where inefficiencies delay care and strain clinician-patient relationships. She notes that ambient AI is already improving accuracy and saving hours for physicians, with the next wave extending into orders, workflows, and care coordination.
However, she emphasizes that successful adoption depends on clinician involvement, intuitive design, and minimizing workflow friction. While AI may take on more clinical decision-making, questions around trust, liability, and human oversight remain central, making it critical for healthcare leaders to actively shape, not resist, this transformation. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Adoption in Healthcare Must Be Led by Clinicians]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital" href="https://soundcloud.com/thebigunlock/dr-ruchi-garg-chief-medical" target="_blank" rel="noreferrer noopener">Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital</a>
<p>In this episode, Dr. Ruchi Garg, Chief Medical Officer at Fairview Park Hospital, shares how frontline clinicians are shaping the responsible adoption of AI in real-world care settings. Dr. Garg highlights how COVID accelerated digital adoption, from telehealth to remote patient monitoring, demonstrating that care can be both accessible and efficient when technology is thoughtfully applied.</p>
<p>Dr. Garg underscores that AI’s true value lies in reducing administrative burden, particularly in areas like documentation and prior authorization, where inefficiencies delay care and strain clinician-patient relationships. She notes that ambient AI is already improving accuracy and saving hours for physicians, with the next wave extending into orders, workflows, and care coordination.</p>
<p>However, she emphasizes that successful adoption depends on clinician involvement, intuitive design, and minimizing workflow friction. While AI may take on more clinical decision-making, questions around trust, liability, and human oversight remain central, making it critical for healthcare leaders to actively shape, not resist, this transformation. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at <a href="https://hlth.com/about-us"><strong>ViVE</strong></a>.</em></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2431411/c1e-jk44a44d2xin1zd6-1p254306fowp-3wqvbq.mp3" length="22620999"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital
In this episode, Dr. Ruchi Garg, Chief Medical Officer at Fairview Park Hospital, shares how frontline clinicians are shaping the responsible adoption of AI in real-world care settings. Dr. Garg highlights how COVID accelerated digital adoption, from telehealth to remote patient monitoring, demonstrating that care can be both accessible and efficient when technology is thoughtfully applied.
Dr. Garg underscores that AI’s true value lies in reducing administrative burden, particularly in areas like documentation and prior authorization, where inefficiencies delay care and strain clinician-patient relationships. She notes that ambient AI is already improving accuracy and saving hours for physicians, with the next wave extending into orders, workflows, and care coordination.
However, she emphasizes that successful adoption depends on clinician involvement, intuitive design, and minimizing workflow friction. While AI may take on more clinical decision-making, questions around trust, liability, and human oversight remain central, making it critical for healthcare leaders to actively shape, not resist, this transformation. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2431411/c1a-gd22-345mr37rcm5r-fo3vbq.png"></itunes:image>
                                                                            <itunes:duration>00:23:34</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Should Make Healthcare Feel More Human]]>
                </title>
                <pubDate>Tue, 28 Apr 2026 07:50:11 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2427844</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-should-make-healthcare-feel-more-human</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Ed Lee, MD, MPH, Chief Medical Officer, Nabla" href="https://soundcloud.com/thebigunlock/ed-lee-md-mph-chief-medical" target="_blank" rel="noreferrer noopener">Ed Lee, MD, MPH, Chief Medical Officer, Nabla</a>
<p>In this episode, Dr. Ed Lee, Chief Medical Officer at Nabla, shares how AI is moving beyond hype to reshape real-world care delivery. Drawing on his experience at Kaiser Permanente, he emphasizes that the true goal of technology is not efficiency alone, but restoring the human connection in healthcare.</p>
<p>Dr. Lee explores why change management, not the technology itself, is the hardest part of AI adoption, and why clinician involvement from day one is non-negotiable. He challenges the early narrative around time savings, arguing that the deeper ROI of ambient AI lies in reducing cognitive burden, restoring joy in medicine, and rebuilding the patient-physician relationship. He also looks ahead to the next frontier: clinical decision support, diagnosis capture, and chart summarization woven seamlessly into workflows. Dr. Lee’s closing thought is simple but powerful – done right, AI shouldn’t feel technical. It should feel human. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://www.himss.org/who-we-are/"><em>HIMSS</em></a><em>.</em></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Ed Lee, MD, MPH, Chief Medical Officer, Nabla
In this episode, Dr. Ed Lee, Chief Medical Officer at Nabla, shares how AI is moving beyond hype to reshape real-world care delivery. Drawing on his experience at Kaiser Permanente, he emphasizes that the true goal of technology is not efficiency alone, but restoring the human connection in healthcare.
Dr. Lee explores why change management, not the technology itself, is the hardest part of AI adoption, and why clinician involvement from day one is non-negotiable. He challenges the early narrative around time savings, arguing that the deeper ROI of ambient AI lies in reducing cognitive burden, restoring joy in medicine, and rebuilding the patient-physician relationship. He also looks ahead to the next frontier: clinical decision support, diagnosis capture, and chart summarization woven seamlessly into workflows. Dr. Lee’s closing thought is simple but powerful – done right, AI shouldn’t feel technical. It should feel human. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Should Make Healthcare Feel More Human]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Ed Lee, MD, MPH, Chief Medical Officer, Nabla" href="https://soundcloud.com/thebigunlock/ed-lee-md-mph-chief-medical" target="_blank" rel="noreferrer noopener">Ed Lee, MD, MPH, Chief Medical Officer, Nabla</a>
<p>In this episode, Dr. Ed Lee, Chief Medical Officer at Nabla, shares how AI is moving beyond hype to reshape real-world care delivery. Drawing on his experience at Kaiser Permanente, he emphasizes that the true goal of technology is not efficiency alone, but restoring the human connection in healthcare.</p>
<p>Dr. Lee explores why change management, not the technology itself, is the hardest part of AI adoption, and why clinician involvement from day one is non-negotiable. He challenges the early narrative around time savings, arguing that the deeper ROI of ambient AI lies in reducing cognitive burden, restoring joy in medicine, and rebuilding the patient-physician relationship. He also looks ahead to the next frontier: clinical decision support, diagnosis capture, and chart summarization woven seamlessly into workflows. Dr. Lee’s closing thought is simple but powerful – done right, AI shouldn’t feel technical. It should feel human. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://www.himss.org/who-we-are/"><em>HIMSS</em></a><em>.</em></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2427844/c1e-8m44uvv27xh1d92g-gpj3j48oi3gv-8kvcjk.mp3" length="19970964"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Ed Lee, MD, MPH, Chief Medical Officer, Nabla
In this episode, Dr. Ed Lee, Chief Medical Officer at Nabla, shares how AI is moving beyond hype to reshape real-world care delivery. Drawing on his experience at Kaiser Permanente, he emphasizes that the true goal of technology is not efficiency alone, but restoring the human connection in healthcare.
Dr. Lee explores why change management, not the technology itself, is the hardest part of AI adoption, and why clinician involvement from day one is non-negotiable. He challenges the early narrative around time savings, arguing that the deeper ROI of ambient AI lies in reducing cognitive burden, restoring joy in medicine, and rebuilding the patient-physician relationship. He also looks ahead to the next frontier: clinical decision support, diagnosis capture, and chart summarization woven seamlessly into workflows. Dr. Lee’s closing thought is simple but powerful – done right, AI shouldn’t feel technical. It should feel human. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2427844/c1a-gd22-345mn6d4t0v-eh7l3j.png"></itunes:image>
                                                                            <itunes:duration>00:20:49</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Will Shape Healthcare Through Access and Affordability]]>
                </title>
                <pubDate>Tue, 21 Apr 2026 08:57:41 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2422653</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-will-shape-healthcare-through-access-and-affordability</link>
                                <description>
                                            <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell" href="https://soundcloud.com/thebigunlock/roy-schoenberg-m-d-ceo-aileen" target="_blank" rel="noreferrer noopener">Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell</a>
<p>In this episode, Dr. Roy Schoenberg, CEO of Aileen and Founder and Executive Director of Amwell, reflects on the evolution of telehealth and shares a bold vision for AI’s role in reshaping care delivery. He argues that telehealth has largely been used as a substitute channel for traditional visits, whereas its true potential lies in redistributing expertise and democratizing access to care at scale.</p>
<p>Dr. Schoenberg sees AI becoming the primary entry point to healthcare, guiding patient journeys through intelligent, cost-driven pathways while working in concert with, rather than replacing, clinical systems. Through his new venture, Aileen AI, Dr. Schoenberg introduces a fundamentally different approach to virtual care: building “staying power” in patients’ lives through deeply personalized, relationship-driven AI interactions, for seniors. By focusing on familiarity, trust, and daily engagement—delivered through simple interfaces like phone calls—Aileen aims to address the growing caregiving gap. Ultimately, he emphasizes that while AI adoption will evolve gradually, its role as a foundational layer in healthcare is inevitable. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://www.himss.org/who-we-are/"><em>HIMSS</em></a><em>.</em></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[﻿
The Big Unlock · Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell
In this episode, Dr. Roy Schoenberg, CEO of Aileen and Founder and Executive Director of Amwell, reflects on the evolution of telehealth and shares a bold vision for AI’s role in reshaping care delivery. He argues that telehealth has largely been used as a substitute channel for traditional visits, whereas its true potential lies in redistributing expertise and democratizing access to care at scale.
Dr. Schoenberg sees AI becoming the primary entry point to healthcare, guiding patient journeys through intelligent, cost-driven pathways while working in concert with, rather than replacing, clinical systems. Through his new venture, Aileen AI, Dr. Schoenberg introduces a fundamentally different approach to virtual care: building “staying power” in patients’ lives through deeply personalized, relationship-driven AI interactions, for seniors. By focusing on familiarity, trust, and daily engagement—delivered through simple interfaces like phone calls—Aileen aims to address the growing caregiving gap. Ultimately, he emphasizes that while AI adoption will evolve gradually, its role as a foundational layer in healthcare is inevitable. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Will Shape Healthcare Through Access and Affordability]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell" href="https://soundcloud.com/thebigunlock/roy-schoenberg-m-d-ceo-aileen" target="_blank" rel="noreferrer noopener">Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell</a>
<p>In this episode, Dr. Roy Schoenberg, CEO of Aileen and Founder and Executive Director of Amwell, reflects on the evolution of telehealth and shares a bold vision for AI’s role in reshaping care delivery. He argues that telehealth has largely been used as a substitute channel for traditional visits, whereas its true potential lies in redistributing expertise and democratizing access to care at scale.</p>
<p>Dr. Schoenberg sees AI becoming the primary entry point to healthcare, guiding patient journeys through intelligent, cost-driven pathways while working in concert with, rather than replacing, clinical systems. Through his new venture, Aileen AI, Dr. Schoenberg introduces a fundamentally different approach to virtual care: building “staying power” in patients’ lives through deeply personalized, relationship-driven AI interactions, for seniors. By focusing on familiarity, trust, and daily engagement—delivered through simple interfaces like phone calls—Aileen aims to address the growing caregiving gap. Ultimately, he emphasizes that while AI adoption will evolve gradually, its role as a foundational layer in healthcare is inevitable. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://www.himss.org/who-we-are/"><em>HIMSS</em></a><em>.</em></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2422653/c1e-xmvvu11mjnun7og5-1p2d8xwmakjm-ir3hs3.mp3" length="23339490"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[﻿
The Big Unlock · Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell
In this episode, Dr. Roy Schoenberg, CEO of Aileen and Founder and Executive Director of Amwell, reflects on the evolution of telehealth and shares a bold vision for AI’s role in reshaping care delivery. He argues that telehealth has largely been used as a substitute channel for traditional visits, whereas its true potential lies in redistributing expertise and democratizing access to care at scale.
Dr. Schoenberg sees AI becoming the primary entry point to healthcare, guiding patient journeys through intelligent, cost-driven pathways while working in concert with, rather than replacing, clinical systems. Through his new venture, Aileen AI, Dr. Schoenberg introduces a fundamentally different approach to virtual care: building “staying power” in patients’ lives through deeply personalized, relationship-driven AI interactions, for seniors. By focusing on familiarity, trust, and daily engagement—delivered through simple interfaces like phone calls—Aileen aims to address the growing caregiving gap. Ultimately, he emphasizes that while AI adoption will evolve gradually, its role as a foundational layer in healthcare is inevitable. Take a listen.
This guest appearance was facilitated through conversations initiated at HIMSS.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2422653/c1a-gd22-1p2k2x0xhvkw-ntxnmh.png"></itunes:image>
                                                                            <itunes:duration>00:24:19</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Leadership Starts with a Simplified, Integrated Tech Stack]]>
                </title>
                <pubDate>Tue, 14 Apr 2026 09:13:07 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2421864</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-leadership-starts-with-a-simplified-integrated-tech-stack</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine" href="https://soundcloud.com/thebigunlock/michael-hasselberg-phd-rn" target="_blank" rel="noreferrer noopener">Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine</a>
<p>In this episode, Dr. Michael Hasselberg, Chief Transformation and Digital Officer at Nebraska Medicine, makes a compelling case that sustainable digital transformation in healthcare requires more than technology, it demands the right organizational structure. By unifying IT, innovation, and strategy under a single transformation office, health systems can move from isolated pilots to enterprise-wide impact.</p>
<p>Drawing from his journey across telehealth, mobile apps, VR, and AI, Dr. Hasselberg emphasizes that true transformation is about redesigning systems to deliver the right care at the right time. Nebraska Medicine deploys nearly one new generative AI tool per month, automating capacity management, discharge workflows, and revenue cycle operations. He also highlights the value of real-world innovation units where new technologies are tested with live patients before system-wide deployment.</p>
<p>Dr. Hasselberg’s most provocative insight: the next frontier of AI readiness isn’t a new technology, it’s application rationalization. He argues that to lead in AI and innovation, health systems must simplify their tech stack. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine
In this episode, Dr. Michael Hasselberg, Chief Transformation and Digital Officer at Nebraska Medicine, makes a compelling case that sustainable digital transformation in healthcare requires more than technology, it demands the right organizational structure. By unifying IT, innovation, and strategy under a single transformation office, health systems can move from isolated pilots to enterprise-wide impact.
Drawing from his journey across telehealth, mobile apps, VR, and AI, Dr. Hasselberg emphasizes that true transformation is about redesigning systems to deliver the right care at the right time. Nebraska Medicine deploys nearly one new generative AI tool per month, automating capacity management, discharge workflows, and revenue cycle operations. He also highlights the value of real-world innovation units where new technologies are tested with live patients before system-wide deployment.
Dr. Hasselberg’s most provocative insight: the next frontier of AI readiness isn’t a new technology, it’s application rationalization. He argues that to lead in AI and innovation, health systems must simplify their tech stack. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Leadership Starts with a Simplified, Integrated Tech Stack]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine" href="https://soundcloud.com/thebigunlock/michael-hasselberg-phd-rn" target="_blank" rel="noreferrer noopener">Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine</a>
<p>In this episode, Dr. Michael Hasselberg, Chief Transformation and Digital Officer at Nebraska Medicine, makes a compelling case that sustainable digital transformation in healthcare requires more than technology, it demands the right organizational structure. By unifying IT, innovation, and strategy under a single transformation office, health systems can move from isolated pilots to enterprise-wide impact.</p>
<p>Drawing from his journey across telehealth, mobile apps, VR, and AI, Dr. Hasselberg emphasizes that true transformation is about redesigning systems to deliver the right care at the right time. Nebraska Medicine deploys nearly one new generative AI tool per month, automating capacity management, discharge workflows, and revenue cycle operations. He also highlights the value of real-world innovation units where new technologies are tested with live patients before system-wide deployment.</p>
<p>Dr. Hasselberg’s most provocative insight: the next frontier of AI readiness isn’t a new technology, it’s application rationalization. He argues that to lead in AI and innovation, health systems must simplify their tech stack. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2421864/c1e-jk44a442rwsn1zd6-dmj5np8paxw6-uxuwbl.mp3" length="26021217"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine
In this episode, Dr. Michael Hasselberg, Chief Transformation and Digital Officer at Nebraska Medicine, makes a compelling case that sustainable digital transformation in healthcare requires more than technology, it demands the right organizational structure. By unifying IT, innovation, and strategy under a single transformation office, health systems can move from isolated pilots to enterprise-wide impact.
Drawing from his journey across telehealth, mobile apps, VR, and AI, Dr. Hasselberg emphasizes that true transformation is about redesigning systems to deliver the right care at the right time. Nebraska Medicine deploys nearly one new generative AI tool per month, automating capacity management, discharge workflows, and revenue cycle operations. He also highlights the value of real-world innovation units where new technologies are tested with live patients before system-wide deployment.
Dr. Hasselberg’s most provocative insight: the next frontier of AI readiness isn’t a new technology, it’s application rationalization. He argues that to lead in AI and innovation, health systems must simplify their tech stack. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2421864/c1a-gd22-7z8kvjo7c6x-fhqau9.png"></itunes:image>
                                                                            <itunes:duration>00:27:07</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Healthcare Needs Real Disruption, Not Incremental Change]]>
                </title>
                <pubDate>Tue, 07 Apr 2026 10:02:51 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2412220</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/healthcare-needs-real-disruption-not-incremental-change</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Stephen K. Klasko, Executive in Residence, General Catalyst &amp; Board Chair, DocGo, Teleflex" href="https://soundcloud.com/thebigunlock/dr-stephen-k-klasko-executive" target="_blank" rel="noreferrer noopener">Dr. Stephen K. Klasko, Executive in Residence, General Catalyst &amp; Board Chair, DocGo, Teleflex</a>
<p>In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo, Teleflex, and one of healthcare’s most provocative voices, challenges the industry to rethink its fundamental assumptions and move toward a more sustainable, patient-centered future. He argues that despite years of discussion around value-based care and digital transformation, true disruption has been limited because stakeholders remain unwilling to fundamentally change existing business models.</p>
<p>Dr. Klasko argues that the healthcare system is broken, fragmented, expensive, and inequitable and that true disruption, like what Uber did to taxis or Amazon to retail, will demand that some players fail. He makes the case that the annual physical visit is a farce, and that continuous health narratives powered by wearables and AI companions are the future of proactive, personalized care.</p>
<p>On the tech-provider collaboration front, Dr. Klasko identifies – founder ego, misaligned incentives, and EHR-era skepticism as the biggest barriers. He advocates for co-developing solutions, sharing equity, and building genuine partnerships. Dr. Klasko’s message to healthcare leaders is unambiguous: stop turning things around 360 degrees and start making real, uncomfortable changes. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://healthtechsummit.ai/"><strong><em>Health Tech Summit by Cornell Tech</em></strong></a><strong><em>.</em></strong></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Dr. Stephen K. Klasko, Executive in Residence, General Catalyst & Board Chair, DocGo, Teleflex
In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo, Teleflex, and one of healthcare’s most provocative voices, challenges the industry to rethink its fundamental assumptions and move toward a more sustainable, patient-centered future. He argues that despite years of discussion around value-based care and digital transformation, true disruption has been limited because stakeholders remain unwilling to fundamentally change existing business models.
Dr. Klasko argues that the healthcare system is broken, fragmented, expensive, and inequitable and that true disruption, like what Uber did to taxis or Amazon to retail, will demand that some players fail. He makes the case that the annual physical visit is a farce, and that continuous health narratives powered by wearables and AI companions are the future of proactive, personalized care.
On the tech-provider collaboration front, Dr. Klasko identifies – founder ego, misaligned incentives, and EHR-era skepticism as the biggest barriers. He advocates for co-developing solutions, sharing equity, and building genuine partnerships. Dr. Klasko’s message to healthcare leaders is unambiguous: stop turning things around 360 degrees and start making real, uncomfortable changes. Take a listen.
This guest appearance was facilitated through conversations initiated at Health Tech Summit by Cornell Tech.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Healthcare Needs Real Disruption, Not Incremental Change]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Stephen K. Klasko, Executive in Residence, General Catalyst &amp; Board Chair, DocGo, Teleflex" href="https://soundcloud.com/thebigunlock/dr-stephen-k-klasko-executive" target="_blank" rel="noreferrer noopener">Dr. Stephen K. Klasko, Executive in Residence, General Catalyst &amp; Board Chair, DocGo, Teleflex</a>
<p>In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo, Teleflex, and one of healthcare’s most provocative voices, challenges the industry to rethink its fundamental assumptions and move toward a more sustainable, patient-centered future. He argues that despite years of discussion around value-based care and digital transformation, true disruption has been limited because stakeholders remain unwilling to fundamentally change existing business models.</p>
<p>Dr. Klasko argues that the healthcare system is broken, fragmented, expensive, and inequitable and that true disruption, like what Uber did to taxis or Amazon to retail, will demand that some players fail. He makes the case that the annual physical visit is a farce, and that continuous health narratives powered by wearables and AI companions are the future of proactive, personalized care.</p>
<p>On the tech-provider collaboration front, Dr. Klasko identifies – founder ego, misaligned incentives, and EHR-era skepticism as the biggest barriers. He advocates for co-developing solutions, sharing equity, and building genuine partnerships. Dr. Klasko’s message to healthcare leaders is unambiguous: stop turning things around 360 degrees and start making real, uncomfortable changes. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at </em><a href="https://healthtechsummit.ai/"><strong><em>Health Tech Summit by Cornell Tech</em></strong></a><strong><em>.</em></strong></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2412220/c1e-qxrru7dx04s0vkd3-mkg3qnk8t3rv-3xbofz.mp3" length="21375837"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Dr. Stephen K. Klasko, Executive in Residence, General Catalyst & Board Chair, DocGo, Teleflex
In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo, Teleflex, and one of healthcare’s most provocative voices, challenges the industry to rethink its fundamental assumptions and move toward a more sustainable, patient-centered future. He argues that despite years of discussion around value-based care and digital transformation, true disruption has been limited because stakeholders remain unwilling to fundamentally change existing business models.
Dr. Klasko argues that the healthcare system is broken, fragmented, expensive, and inequitable and that true disruption, like what Uber did to taxis or Amazon to retail, will demand that some players fail. He makes the case that the annual physical visit is a farce, and that continuous health narratives powered by wearables and AI companions are the future of proactive, personalized care.
On the tech-provider collaboration front, Dr. Klasko identifies – founder ego, misaligned incentives, and EHR-era skepticism as the biggest barriers. He advocates for co-developing solutions, sharing equity, and building genuine partnerships. Dr. Klasko’s message to healthcare leaders is unambiguous: stop turning things around 360 degrees and start making real, uncomfortable changes. Take a listen.
This guest appearance was facilitated through conversations initiated at Health Tech Summit by Cornell Tech.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2412220/c1a-gd22-47ov0d6xi511-ilhh8h.png"></itunes:image>
                                                                            <itunes:duration>00:22:16</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Autonomous AI Turning Evidence into Action]]>
                </title>
                <pubDate>Wed, 01 Apr 2026 04:49:54 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2410136</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/autonomous-ai-turning-evidence-into-action</link>
                                <description>
                                            <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health" href="https://soundcloud.com/thebigunlock/dr-eric-stecker-co-founder-and" target="_blank" rel="noreferrer noopener">Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health</a>
<p>In this episode, Dr. Eric Stecker, Co-founder and Chief Medical Officer at Insight Health, explores how autonomous AI agents are reshaping cardiovascular care and population health in the United States.</p>
<p>Dr. Stecker draws a critical distinction between autonomous action and autonomous decision-making, arguing that AI can deliver enormous clinical value today by acting autonomously on well-established care protocols, without waiting for fully autonomous diagnostic AI. He highlights that preventable conditions like hypertension and high cholesterol already have decades of evidence behind them; the real gap is in implementation, where AI-powered agents can identify at-risk patients, prompt appropriate prescriptions, and check in on medication adherence by reducing millions of avoidable cardiac events.</p>
<p>Dr. Stecker emphasizes that clinician involvement, not just advisory oversight, is essential to avoid alert fatigue, documentation overload, and signal-to-noise failures. He states that meaningful AI adoption requires building trust with both healthcare workers and patients, starting with autonomous action today while responsibly advancing toward autonomous clinical decision-making tomorrow. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at <strong>ViVE</strong>. </em></p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[﻿
The Big Unlock · Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health
In this episode, Dr. Eric Stecker, Co-founder and Chief Medical Officer at Insight Health, explores how autonomous AI agents are reshaping cardiovascular care and population health in the United States.
Dr. Stecker draws a critical distinction between autonomous action and autonomous decision-making, arguing that AI can deliver enormous clinical value today by acting autonomously on well-established care protocols, without waiting for fully autonomous diagnostic AI. He highlights that preventable conditions like hypertension and high cholesterol already have decades of evidence behind them; the real gap is in implementation, where AI-powered agents can identify at-risk patients, prompt appropriate prescriptions, and check in on medication adherence by reducing millions of avoidable cardiac events.
Dr. Stecker emphasizes that clinician involvement, not just advisory oversight, is essential to avoid alert fatigue, documentation overload, and signal-to-noise failures. He states that meaningful AI adoption requires building trust with both healthcare workers and patients, starting with autonomous action today while responsibly advancing toward autonomous clinical decision-making tomorrow. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE. ]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Autonomous AI Turning Evidence into Action]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health" href="https://soundcloud.com/thebigunlock/dr-eric-stecker-co-founder-and" target="_blank" rel="noreferrer noopener">Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health</a>
<p>In this episode, Dr. Eric Stecker, Co-founder and Chief Medical Officer at Insight Health, explores how autonomous AI agents are reshaping cardiovascular care and population health in the United States.</p>
<p>Dr. Stecker draws a critical distinction between autonomous action and autonomous decision-making, arguing that AI can deliver enormous clinical value today by acting autonomously on well-established care protocols, without waiting for fully autonomous diagnostic AI. He highlights that preventable conditions like hypertension and high cholesterol already have decades of evidence behind them; the real gap is in implementation, where AI-powered agents can identify at-risk patients, prompt appropriate prescriptions, and check in on medication adherence by reducing millions of avoidable cardiac events.</p>
<p>Dr. Stecker emphasizes that clinician involvement, not just advisory oversight, is essential to avoid alert fatigue, documentation overload, and signal-to-noise failures. He states that meaningful AI adoption requires building trust with both healthcare workers and patients, starting with autonomous action today while responsibly advancing toward autonomous clinical decision-making tomorrow. Take a listen.</p>
<p><em>This guest appearance was facilitated through conversations initiated at <strong>ViVE</strong>. </em></p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2410136/c1e-mq00a4qdqdcwqd0p-8d0k217xhrox-ss0ecp.mp3" length="23929962"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[﻿
The Big Unlock · Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health
In this episode, Dr. Eric Stecker, Co-founder and Chief Medical Officer at Insight Health, explores how autonomous AI agents are reshaping cardiovascular care and population health in the United States.
Dr. Stecker draws a critical distinction between autonomous action and autonomous decision-making, arguing that AI can deliver enormous clinical value today by acting autonomously on well-established care protocols, without waiting for fully autonomous diagnostic AI. He highlights that preventable conditions like hypertension and high cholesterol already have decades of evidence behind them; the real gap is in implementation, where AI-powered agents can identify at-risk patients, prompt appropriate prescriptions, and check in on medication adherence by reducing millions of avoidable cardiac events.
Dr. Stecker emphasizes that clinician involvement, not just advisory oversight, is essential to avoid alert fatigue, documentation overload, and signal-to-noise failures. He states that meaningful AI adoption requires building trust with both healthcare workers and patients, starting with autonomous action today while responsibly advancing toward autonomous clinical decision-making tomorrow. Take a listen.
This guest appearance was facilitated through conversations initiated at ViVE. ]]>
                </itunes:summary>
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                                                                            <itunes:duration>00:24:56</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Moving Beyond Pilots to Scale Impact in Healthcare]]>
                </title>
                <pubDate>Tue, 24 Mar 2026 09:05:07 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2404241</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/moving-beyond-pilots-to-scale-impact-in-healthcare</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures, Tampa General Hospital" href="https://soundcloud.com/thebigunlock/rachel-feinman-svp-of" target="_blank" rel="noreferrer noopener">Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures, Tampa General Hospital</a>
<p>In this episode, Rachel Feinman, SVP of Innovation and Managing Director, TGH Ventures at Tampa General Hospital, shares how the organization is breaking out of “pilot purgatory” to turn digital innovation into measurable impact. With a clear mandate to move beyond endless experimentation, the focus is on starting with a strong thesis, partnering intentionally, and scaling quickly when results are proven.</p>
<p>Rachel reflects on her journey from law to healthcare, bringing a unique lens on strategy, execution, and deal-making. She highlights the balance healthcare must strike that is moving fast in operational and administrative workflows while taking a deliberate, governance-led approach to clinical innovation. This “go slow to go fast” mindset enables both safety and speed.</p>
<p>She also underscores the growing role of AI in improving logistics, supporting care teams, and unlocking real-time insights, while emphasizing responsible deployment. Beyond technology, the real opportunity lies in connecting fragmented care journeys and extending care beyond hospital walls to create a more seamless, patient-centered experience. Through strategic investments and a focus on outcomes, Tampa General is building an innovation model designed to scale impact, not just ideas. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures, Tampa General Hospital
In this episode, Rachel Feinman, SVP of Innovation and Managing Director, TGH Ventures at Tampa General Hospital, shares how the organization is breaking out of “pilot purgatory” to turn digital innovation into measurable impact. With a clear mandate to move beyond endless experimentation, the focus is on starting with a strong thesis, partnering intentionally, and scaling quickly when results are proven.
Rachel reflects on her journey from law to healthcare, bringing a unique lens on strategy, execution, and deal-making. She highlights the balance healthcare must strike that is moving fast in operational and administrative workflows while taking a deliberate, governance-led approach to clinical innovation. This “go slow to go fast” mindset enables both safety and speed.
She also underscores the growing role of AI in improving logistics, supporting care teams, and unlocking real-time insights, while emphasizing responsible deployment. Beyond technology, the real opportunity lies in connecting fragmented care journeys and extending care beyond hospital walls to create a more seamless, patient-centered experience. Through strategic investments and a focus on outcomes, Tampa General is building an innovation model designed to scale impact, not just ideas. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Moving Beyond Pilots to Scale Impact in Healthcare]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures, Tampa General Hospital" href="https://soundcloud.com/thebigunlock/rachel-feinman-svp-of" target="_blank" rel="noreferrer noopener">Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures, Tampa General Hospital</a>
<p>In this episode, Rachel Feinman, SVP of Innovation and Managing Director, TGH Ventures at Tampa General Hospital, shares how the organization is breaking out of “pilot purgatory” to turn digital innovation into measurable impact. With a clear mandate to move beyond endless experimentation, the focus is on starting with a strong thesis, partnering intentionally, and scaling quickly when results are proven.</p>
<p>Rachel reflects on her journey from law to healthcare, bringing a unique lens on strategy, execution, and deal-making. She highlights the balance healthcare must strike that is moving fast in operational and administrative workflows while taking a deliberate, governance-led approach to clinical innovation. This “go slow to go fast” mindset enables both safety and speed.</p>
<p>She also underscores the growing role of AI in improving logistics, supporting care teams, and unlocking real-time insights, while emphasizing responsible deployment. Beyond technology, the real opportunity lies in connecting fragmented care journeys and extending care beyond hospital walls to create a more seamless, patient-centered experience. Through strategic investments and a focus on outcomes, Tampa General is building an innovation model designed to scale impact, not just ideas. Take a listen.</p>]]>
                </content:encoded>
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                        type="audio/mpeg">
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                                <itunes:summary>
                    <![CDATA[The Big Unlock · Rachel Feinman, SVP of Innovation and Managing Director of TGH Ventures, Tampa General Hospital
In this episode, Rachel Feinman, SVP of Innovation and Managing Director, TGH Ventures at Tampa General Hospital, shares how the organization is breaking out of “pilot purgatory” to turn digital innovation into measurable impact. With a clear mandate to move beyond endless experimentation, the focus is on starting with a strong thesis, partnering intentionally, and scaling quickly when results are proven.
Rachel reflects on her journey from law to healthcare, bringing a unique lens on strategy, execution, and deal-making. She highlights the balance healthcare must strike that is moving fast in operational and administrative workflows while taking a deliberate, governance-led approach to clinical innovation. This “go slow to go fast” mindset enables both safety and speed.
She also underscores the growing role of AI in improving logistics, supporting care teams, and unlocking real-time insights, while emphasizing responsible deployment. Beyond technology, the real opportunity lies in connecting fragmented care journeys and extending care beyond hospital walls to create a more seamless, patient-centered experience. Through strategic investments and a focus on outcomes, Tampa General is building an innovation model designed to scale impact, not just ideas. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2404241/c1a-gd22-jpqr4k59u73-zghxuz.png"></itunes:image>
                                                                            <itunes:duration>00:20:32</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Turning AI Hype into Healthcare Execution]]>
                </title>
                <pubDate>Mon, 02 Mar 2026 11:37:36 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2380475</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/turning-ai-hype-into-healthcare-execution</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Aditya Bansod, CTO &amp; Co-Founder, Luma Health" href="https://soundcloud.com/thebigunlock/aditya-bansod-cto-co-founder" target="_blank" rel="noreferrer noopener">Aditya Bansod, CTO &amp; Co-Founder, Luma Health</a>
<p>In this episode, Aditya Bansod, CTO and Co-Founder of Luma Health, about why healthcare AI often underdelivers — and what leaders must do to turn promise into performance.</p>
<p>Aditya argues that AI’s challenge in healthcare isn’t ambition, but execution. While new tools are emerging rapidly, most remain point solutions that fail to integrate into the complex workflows that move patients from scheduling to care delivery. True impact, he says, depends on orchestrating the “last mile” of healthcare, referrals, intake, documentation, and the countless operational handoffs that determine whether care actually happens.</p>
<p>He shares how Luma approaches AI adoption with flexible guardrails, allowing health systems to calibrate automation based on confidence thresholds and maturity. The conversation also explores the rise of agentic AI, the tension between human-in-the-loop oversight and autonomy, and why CIOs are navigating a messy but necessary consolidation phase.</p>
<p>Looking ahead, Aditya is optimistic that AI will transform patient access and engagement, only if it’s deeply embedded into workflows, not layered on top of them. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Aditya Bansod, CTO & Co-Founder, Luma Health
In this episode, Aditya Bansod, CTO and Co-Founder of Luma Health, about why healthcare AI often underdelivers — and what leaders must do to turn promise into performance.
Aditya argues that AI’s challenge in healthcare isn’t ambition, but execution. While new tools are emerging rapidly, most remain point solutions that fail to integrate into the complex workflows that move patients from scheduling to care delivery. True impact, he says, depends on orchestrating the “last mile” of healthcare, referrals, intake, documentation, and the countless operational handoffs that determine whether care actually happens.
He shares how Luma approaches AI adoption with flexible guardrails, allowing health systems to calibrate automation based on confidence thresholds and maturity. The conversation also explores the rise of agentic AI, the tension between human-in-the-loop oversight and autonomy, and why CIOs are navigating a messy but necessary consolidation phase.
Looking ahead, Aditya is optimistic that AI will transform patient access and engagement, only if it’s deeply embedded into workflows, not layered on top of them. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Turning AI Hype into Healthcare Execution]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Aditya Bansod, CTO &amp; Co-Founder, Luma Health" href="https://soundcloud.com/thebigunlock/aditya-bansod-cto-co-founder" target="_blank" rel="noreferrer noopener">Aditya Bansod, CTO &amp; Co-Founder, Luma Health</a>
<p>In this episode, Aditya Bansod, CTO and Co-Founder of Luma Health, about why healthcare AI often underdelivers — and what leaders must do to turn promise into performance.</p>
<p>Aditya argues that AI’s challenge in healthcare isn’t ambition, but execution. While new tools are emerging rapidly, most remain point solutions that fail to integrate into the complex workflows that move patients from scheduling to care delivery. True impact, he says, depends on orchestrating the “last mile” of healthcare, referrals, intake, documentation, and the countless operational handoffs that determine whether care actually happens.</p>
<p>He shares how Luma approaches AI adoption with flexible guardrails, allowing health systems to calibrate automation based on confidence thresholds and maturity. The conversation also explores the rise of agentic AI, the tension between human-in-the-loop oversight and autonomy, and why CIOs are navigating a messy but necessary consolidation phase.</p>
<p>Looking ahead, Aditya is optimistic that AI will transform patient access and engagement, only if it’s deeply embedded into workflows, not layered on top of them. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2380475/c1e-8m44uvxx4pt1d92g-5z3wq46mcmw8-ytpikk.mp3" length="23898270"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Aditya Bansod, CTO & Co-Founder, Luma Health
In this episode, Aditya Bansod, CTO and Co-Founder of Luma Health, about why healthcare AI often underdelivers — and what leaders must do to turn promise into performance.
Aditya argues that AI’s challenge in healthcare isn’t ambition, but execution. While new tools are emerging rapidly, most remain point solutions that fail to integrate into the complex workflows that move patients from scheduling to care delivery. True impact, he says, depends on orchestrating the “last mile” of healthcare, referrals, intake, documentation, and the countless operational handoffs that determine whether care actually happens.
He shares how Luma approaches AI adoption with flexible guardrails, allowing health systems to calibrate automation based on confidence thresholds and maturity. The conversation also explores the rise of agentic AI, the tension between human-in-the-loop oversight and autonomy, and why CIOs are navigating a messy but necessary consolidation phase.
Looking ahead, Aditya is optimistic that AI will transform patient access and engagement, only if it’s deeply embedded into workflows, not layered on top of them. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2380475/c1a-gd22-47ow4p0ki3j7-mnkp1q.png"></itunes:image>
                                                                            <itunes:duration>00:24:54</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Augmenting Care and Strengthening Trust with AI]]>
                </title>
                <pubDate>Thu, 19 Feb 2026 16:00:10 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
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                                    <link>https://the-big-unlock.castos.com/episodes/augmenting-care-and-strengthening-trust-with-ai</link>
                                <description>
                                            <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Andrea Willis, SVP &amp; Chief Medical Officer, BlueCross BlueShield of Tennessee" href="https://soundcloud.com/thebigunlock/dr-andrea-willis-svp-and-chief-medical-officer-bluecross-blueshield-of-tennessee" target="_blank" rel="noreferrer noopener">Dr. Andrea Willis, SVP &amp; Chief Medical Officer, BlueCross BlueShield of Tennessee</a>
<p>In this episode, Dr. Andrea Willis, SVP and Chief Medical Officer at BlueCross BlueShield of Tennessee, shares how payers can harness AI to advance affordable, accessible, and more human-centered care.</p>
<p>From her clinical roots to leading population health, quality, and health equity initiatives, Dr. Willis brings a deeply personal commitment to service. She describes how AI is being deployed across care management and utilization management, not to replace clinicians or deny care, but to augment teams, accelerate evidence-based decisions, and close gaps in care. In care management, AI-powered summarization and prompting help staff stay fully present with members while improving engagement and measurable outcomes. In utilization management, transparency, evidence-based criteria, and clear documentation remain foundational to rebuilding provider trust. She also highlights that relevance matters more than data volume, and that guided self-service must balance automation with timely human escalation.</p>
<p>Dr. Willis emphasizes transparency in prior authorization, cross-functional governance, AI literacy goals across the enterprise, and strong PHI protections. For here, scaling AI responsibly – through interoperability, collaboration, and measurable impact – is key to rebuilding trust and transforming the healthcare experience. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[﻿
The Big Unlock · Dr. Andrea Willis, SVP & Chief Medical Officer, BlueCross BlueShield of Tennessee
In this episode, Dr. Andrea Willis, SVP and Chief Medical Officer at BlueCross BlueShield of Tennessee, shares how payers can harness AI to advance affordable, accessible, and more human-centered care.
From her clinical roots to leading population health, quality, and health equity initiatives, Dr. Willis brings a deeply personal commitment to service. She describes how AI is being deployed across care management and utilization management, not to replace clinicians or deny care, but to augment teams, accelerate evidence-based decisions, and close gaps in care. In care management, AI-powered summarization and prompting help staff stay fully present with members while improving engagement and measurable outcomes. In utilization management, transparency, evidence-based criteria, and clear documentation remain foundational to rebuilding provider trust. She also highlights that relevance matters more than data volume, and that guided self-service must balance automation with timely human escalation.
Dr. Willis emphasizes transparency in prior authorization, cross-functional governance, AI literacy goals across the enterprise, and strong PHI protections. For here, scaling AI responsibly – through interoperability, collaboration, and measurable impact – is key to rebuilding trust and transforming the healthcare experience. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Augmenting Care and Strengthening Trust with AI]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Andrea Willis, SVP &amp; Chief Medical Officer, BlueCross BlueShield of Tennessee" href="https://soundcloud.com/thebigunlock/dr-andrea-willis-svp-and-chief-medical-officer-bluecross-blueshield-of-tennessee" target="_blank" rel="noreferrer noopener">Dr. Andrea Willis, SVP &amp; Chief Medical Officer, BlueCross BlueShield of Tennessee</a>
<p>In this episode, Dr. Andrea Willis, SVP and Chief Medical Officer at BlueCross BlueShield of Tennessee, shares how payers can harness AI to advance affordable, accessible, and more human-centered care.</p>
<p>From her clinical roots to leading population health, quality, and health equity initiatives, Dr. Willis brings a deeply personal commitment to service. She describes how AI is being deployed across care management and utilization management, not to replace clinicians or deny care, but to augment teams, accelerate evidence-based decisions, and close gaps in care. In care management, AI-powered summarization and prompting help staff stay fully present with members while improving engagement and measurable outcomes. In utilization management, transparency, evidence-based criteria, and clear documentation remain foundational to rebuilding provider trust. She also highlights that relevance matters more than data volume, and that guided self-service must balance automation with timely human escalation.</p>
<p>Dr. Willis emphasizes transparency in prior authorization, cross-functional governance, AI literacy goals across the enterprise, and strong PHI protections. For here, scaling AI responsibly – through interoperability, collaboration, and measurable impact – is key to rebuilding trust and transforming the healthcare experience. Take a listen.</p>]]>
                </content:encoded>
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                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[﻿
The Big Unlock · Dr. Andrea Willis, SVP & Chief Medical Officer, BlueCross BlueShield of Tennessee
In this episode, Dr. Andrea Willis, SVP and Chief Medical Officer at BlueCross BlueShield of Tennessee, shares how payers can harness AI to advance affordable, accessible, and more human-centered care.
From her clinical roots to leading population health, quality, and health equity initiatives, Dr. Willis brings a deeply personal commitment to service. She describes how AI is being deployed across care management and utilization management, not to replace clinicians or deny care, but to augment teams, accelerate evidence-based decisions, and close gaps in care. In care management, AI-powered summarization and prompting help staff stay fully present with members while improving engagement and measurable outcomes. In utilization management, transparency, evidence-based criteria, and clear documentation remain foundational to rebuilding provider trust. She also highlights that relevance matters more than data volume, and that guided self-service must balance automation with timely human escalation.
Dr. Willis emphasizes transparency in prior authorization, cross-functional governance, AI literacy goals across the enterprise, and strong PHI protections. For here, scaling AI responsibly – through interoperability, collaboration, and measurable impact – is key to rebuilding trust and transforming the healthcare experience. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2367961/c1a-gd22-xx7rrpv0fr68-fas03m.png"></itunes:image>
                                                                            <itunes:duration>00:23:36</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Must Strengthen a Clinician’s “Spidey Sense,” Not Replace It]]>
                </title>
                <pubDate>Wed, 04 Feb 2026 10:20:11 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2347835</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-must-strengthen-a-clinicians-spidey-sense-not-replace-it</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Amit Phull, Chief Clinical Experience Officer, Doximity" href="https://soundcloud.com/thebigunlock/dr-amit-phull-chief-clinical-experience-officer-doximity" target="_blank" rel="noreferrer noopener">Dr. Amit Phull, Chief Clinical Experience Officer, Doximity</a>
<p>In this episode, Dr. Amit Phull discusses what responsible AI adoption in healthcare really looks like, starting with trust, usability, and preserving clinician judgment. He emphasizes that ease of use and confidence in outputs are non-negotiable for clinician adoption, especially in already time-constrained workflows.</p>
<p>The discussion also explores why AI must be built with clinicians, not simply deployed for them, and how poorly integrated tools risk adding friction instead of value. Dr. Phull also talks about preserving a clinician’s “spidey sense”—the intuition developed through experience—while using AI to augment, not override, clinical judgment. The conversation also touches on how success should be measured beyond dashboards, including recurrent use, time savings, and reductions in burnout.</p>
<p>Dr. Phull states that AI, when designed thoughtfully, can help clinicians reclaim time, sharpen expertise, and focus more fully on patient care, without losing the human edge that defines great medicine. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Dr. Amit Phull, Chief Clinical Experience Officer, Doximity
In this episode, Dr. Amit Phull discusses what responsible AI adoption in healthcare really looks like, starting with trust, usability, and preserving clinician judgment. He emphasizes that ease of use and confidence in outputs are non-negotiable for clinician adoption, especially in already time-constrained workflows.
The discussion also explores why AI must be built with clinicians, not simply deployed for them, and how poorly integrated tools risk adding friction instead of value. Dr. Phull also talks about preserving a clinician’s “spidey sense”—the intuition developed through experience—while using AI to augment, not override, clinical judgment. The conversation also touches on how success should be measured beyond dashboards, including recurrent use, time savings, and reductions in burnout.
Dr. Phull states that AI, when designed thoughtfully, can help clinicians reclaim time, sharpen expertise, and focus more fully on patient care, without losing the human edge that defines great medicine. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Must Strengthen a Clinician’s “Spidey Sense,” Not Replace It]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Amit Phull, Chief Clinical Experience Officer, Doximity" href="https://soundcloud.com/thebigunlock/dr-amit-phull-chief-clinical-experience-officer-doximity" target="_blank" rel="noreferrer noopener">Dr. Amit Phull, Chief Clinical Experience Officer, Doximity</a>
<p>In this episode, Dr. Amit Phull discusses what responsible AI adoption in healthcare really looks like, starting with trust, usability, and preserving clinician judgment. He emphasizes that ease of use and confidence in outputs are non-negotiable for clinician adoption, especially in already time-constrained workflows.</p>
<p>The discussion also explores why AI must be built with clinicians, not simply deployed for them, and how poorly integrated tools risk adding friction instead of value. Dr. Phull also talks about preserving a clinician’s “spidey sense”—the intuition developed through experience—while using AI to augment, not override, clinical judgment. The conversation also touches on how success should be measured beyond dashboards, including recurrent use, time savings, and reductions in burnout.</p>
<p>Dr. Phull states that AI, when designed thoughtfully, can help clinicians reclaim time, sharpen expertise, and focus more fully on patient care, without losing the human edge that defines great medicine. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2347835/c1e-2odduq9gjvc678wz-ww7458vxsvdw-zhucxe.mp3" length="25462437"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Dr. Amit Phull, Chief Clinical Experience Officer, Doximity
In this episode, Dr. Amit Phull discusses what responsible AI adoption in healthcare really looks like, starting with trust, usability, and preserving clinician judgment. He emphasizes that ease of use and confidence in outputs are non-negotiable for clinician adoption, especially in already time-constrained workflows.
The discussion also explores why AI must be built with clinicians, not simply deployed for them, and how poorly integrated tools risk adding friction instead of value. Dr. Phull also talks about preserving a clinician’s “spidey sense”—the intuition developed through experience—while using AI to augment, not override, clinical judgment. The conversation also touches on how success should be measured beyond dashboards, including recurrent use, time savings, and reductions in burnout.
Dr. Phull states that AI, when designed thoughtfully, can help clinicians reclaim time, sharpen expertise, and focus more fully on patient care, without losing the human edge that defines great medicine. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2347835/c1a-gd22-6z984mxxs56w-ni9ipt.png"></itunes:image>
                                                                            <itunes:duration>00:26:32</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Succeeds Through Seamless Workflow Integration and Clinician Empowerment]]>
                </title>
                <pubDate>Thu, 22 Jan 2026 07:32:27 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2333577</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-succeeds-through-seamless-workflow-integration-and-clinician-empowerment</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Chethan Sathya, MD., Vice President of Strategic Initiatives, Northwell Health" href="https://soundcloud.com/thebigunlock/chethan-sathya-md-vice-president-of-strategic-initiatives-northwell-health" target="_blank" rel="noreferrer noopener">Chethan Sathya, MD., Vice President of Strategic Initiatives, Northwell Health</a>
<p>In this episode, Dr. Chethan Sathya, Vice President of Strategic Initiatives at Northwell Health, unpacks why healthcare innovation only scales when clinicians, public health, and AI are designed to work together.</p>
<p>Dr. Sathya shares his journey from surgery to journalism to public health advocacy, including leading gun violence prevention efforts. He explains why most AI pilots fail, because of poor workflow integration and clinician burden, and why ambient intelligence, tele-specialty care, and agentic AI are poised to scale. His message is clear: build technology alongside clinicians, not around them. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Chethan Sathya, MD., Vice President of Strategic Initiatives, Northwell Health
In this episode, Dr. Chethan Sathya, Vice President of Strategic Initiatives at Northwell Health, unpacks why healthcare innovation only scales when clinicians, public health, and AI are designed to work together.
Dr. Sathya shares his journey from surgery to journalism to public health advocacy, including leading gun violence prevention efforts. He explains why most AI pilots fail, because of poor workflow integration and clinician burden, and why ambient intelligence, tele-specialty care, and agentic AI are poised to scale. His message is clear: build technology alongside clinicians, not around them. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Succeeds Through Seamless Workflow Integration and Clinician Empowerment]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Chethan Sathya, MD., Vice President of Strategic Initiatives, Northwell Health" href="https://soundcloud.com/thebigunlock/chethan-sathya-md-vice-president-of-strategic-initiatives-northwell-health" target="_blank" rel="noreferrer noopener">Chethan Sathya, MD., Vice President of Strategic Initiatives, Northwell Health</a>
<p>In this episode, Dr. Chethan Sathya, Vice President of Strategic Initiatives at Northwell Health, unpacks why healthcare innovation only scales when clinicians, public health, and AI are designed to work together.</p>
<p>Dr. Sathya shares his journey from surgery to journalism to public health advocacy, including leading gun violence prevention efforts. He explains why most AI pilots fail, because of poor workflow integration and clinician burden, and why ambient intelligence, tele-specialty care, and agentic AI are poised to scale. His message is clear: build technology alongside clinicians, not around them. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2333577/c1e-njwwczm082u9z21p-jpq328vzfm3x-gf7xjq.mp3" length="17768370"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Chethan Sathya, MD., Vice President of Strategic Initiatives, Northwell Health
In this episode, Dr. Chethan Sathya, Vice President of Strategic Initiatives at Northwell Health, unpacks why healthcare innovation only scales when clinicians, public health, and AI are designed to work together.
Dr. Sathya shares his journey from surgery to journalism to public health advocacy, including leading gun violence prevention efforts. He explains why most AI pilots fail, because of poor workflow integration and clinician burden, and why ambient intelligence, tele-specialty care, and agentic AI are poised to scale. His message is clear: build technology alongside clinicians, not around them. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2333577/c1a-gd22-5z3o1mxraz9j-cfwzqg.png"></itunes:image>
                                                                            <itunes:duration>00:18:31</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Fixing Healthcare’s “Blind Men and the Elephant” Data Problem]]>
                </title>
                <pubDate>Mon, 12 Jan 2026 10:54:35 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2319887</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/fixing-healthcares-blind-men-and-the-elephant-data-problem</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Jonathan Bush, Founder &amp; CEO, Zus Health" href="https://soundcloud.com/thebigunlock/jonathan-bush-founder-ceo-zus-health" target="_blank" rel="noreferrer noopener">Jonathan Bush, Founder &amp; CEO, Zus Health</a>
<p>In this episode, Jonathan Bush, Founder &amp; CEO of Zus Health, shares a bold vision for the next phase of healthcare transformation. Drawing on decades of experience, Jonathan argues that while EHR adoption is largely complete, today’s systems remain fee-for-service–oriented, creating fragmented views of patients – what he describes as the <em>“blind men and the elephant”</em> problem. The result: clinicians still lack a complete, longitudinal picture of the patient and rely on repeated tests and “bags full of records.”</p>
<p>Jonathan explains how Zus Health is re-architecting healthcare data by creating a longitudinal, always-on common patient record. Zus is an API-first platform built on an AI-enabled backbone that aggregates, structures, and continuously updates data across multiple EMRs. He emphasizes the power of network effects, where shared intelligence can eliminate redundant tests and unnecessary care.</p>
<p>The conversation also explores why interoperability must move beyond regulatory compliance to become core infrastructure for value-based care, and how AI-driven summarization and agentic workflows can reduce clinician burden while enabling proactive, patient-centered care. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Jonathan Bush, Founder & CEO, Zus Health
In this episode, Jonathan Bush, Founder & CEO of Zus Health, shares a bold vision for the next phase of healthcare transformation. Drawing on decades of experience, Jonathan argues that while EHR adoption is largely complete, today’s systems remain fee-for-service–oriented, creating fragmented views of patients – what he describes as the “blind men and the elephant” problem. The result: clinicians still lack a complete, longitudinal picture of the patient and rely on repeated tests and “bags full of records.”
Jonathan explains how Zus Health is re-architecting healthcare data by creating a longitudinal, always-on common patient record. Zus is an API-first platform built on an AI-enabled backbone that aggregates, structures, and continuously updates data across multiple EMRs. He emphasizes the power of network effects, where shared intelligence can eliminate redundant tests and unnecessary care.
The conversation also explores why interoperability must move beyond regulatory compliance to become core infrastructure for value-based care, and how AI-driven summarization and agentic workflows can reduce clinician burden while enabling proactive, patient-centered care. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Fixing Healthcare’s “Blind Men and the Elephant” Data Problem]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Jonathan Bush, Founder &amp; CEO, Zus Health" href="https://soundcloud.com/thebigunlock/jonathan-bush-founder-ceo-zus-health" target="_blank" rel="noreferrer noopener">Jonathan Bush, Founder &amp; CEO, Zus Health</a>
<p>In this episode, Jonathan Bush, Founder &amp; CEO of Zus Health, shares a bold vision for the next phase of healthcare transformation. Drawing on decades of experience, Jonathan argues that while EHR adoption is largely complete, today’s systems remain fee-for-service–oriented, creating fragmented views of patients – what he describes as the <em>“blind men and the elephant”</em> problem. The result: clinicians still lack a complete, longitudinal picture of the patient and rely on repeated tests and “bags full of records.”</p>
<p>Jonathan explains how Zus Health is re-architecting healthcare data by creating a longitudinal, always-on common patient record. Zus is an API-first platform built on an AI-enabled backbone that aggregates, structures, and continuously updates data across multiple EMRs. He emphasizes the power of network effects, where shared intelligence can eliminate redundant tests and unnecessary care.</p>
<p>The conversation also explores why interoperability must move beyond regulatory compliance to become core infrastructure for value-based care, and how AI-driven summarization and agentic workflows can reduce clinician burden while enabling proactive, patient-centered care. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2319887/c1e-2oddumo2doa678wz-8d09pqd9f8dq-ocxs6p.mp3" length="29916414"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Jonathan Bush, Founder & CEO, Zus Health
In this episode, Jonathan Bush, Founder & CEO of Zus Health, shares a bold vision for the next phase of healthcare transformation. Drawing on decades of experience, Jonathan argues that while EHR adoption is largely complete, today’s systems remain fee-for-service–oriented, creating fragmented views of patients – what he describes as the “blind men and the elephant” problem. The result: clinicians still lack a complete, longitudinal picture of the patient and rely on repeated tests and “bags full of records.”
Jonathan explains how Zus Health is re-architecting healthcare data by creating a longitudinal, always-on common patient record. Zus is an API-first platform built on an AI-enabled backbone that aggregates, structures, and continuously updates data across multiple EMRs. He emphasizes the power of network effects, where shared intelligence can eliminate redundant tests and unnecessary care.
The conversation also explores why interoperability must move beyond regulatory compliance to become core infrastructure for value-based care, and how AI-driven summarization and agentic workflows can reduce clinician burden while enabling proactive, patient-centered care. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2319887/c1a-gd22-7zrk6vp8t87w-qsolvo.jpg"></itunes:image>
                                                                            <itunes:duration>00:31:10</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Improves Endpoints and Evidence in Clinical Trials]]>
                </title>
                <pubDate>Wed, 17 Dec 2025 08:13:08 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2292831</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-improves-endpoints-and-evidence-in-clinical-trials</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging &amp; Pathology, Merck Research Laboratories" href="https://soundcloud.com/thebigunlock/gregory-goldmacher-md-associate-vice-president-in-clinical-research-and-head-of-clinical-imaging-pathology-merck-research-laboratories" target="_blank" rel="noreferrer noopener">Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging &amp; Pathology, Merck Research Laboratories</a>
<p>In this episode, Dr. Greg Goldmacher, Associate VP of Clinical Research at Merck, known as MSD outside of the United States and Canada, explains how AI is transforming imaging, clinical trials, and early-stage drug development. Greg describes endpoints as the core of every clinical trial, since they determine whether a therapy is safe or effective. He notes that AI is not new to imaging and aligns well with pattern recognition, yet its real value lies in identifying details that humans often miss.</p>
<p>Greg stresses that drug development still depends on huge volumes of data spread across legacy systems. Without strong data standardization, AI cannot deliver reliable results. He also points to the FDA’s evolving guidance on AI and emphasizes the need for rigorous validation before using AI-derived measurements for regulatory decisions.</p>
<p>Greg highlights the opportunity to improve efficiency, reduce human burden, and generate more consistent insights. With thoughtful adoption, AI can support better decisions in clinical development and improve outcomes for patients. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging & Pathology, Merck Research Laboratories
In this episode, Dr. Greg Goldmacher, Associate VP of Clinical Research at Merck, known as MSD outside of the United States and Canada, explains how AI is transforming imaging, clinical trials, and early-stage drug development. Greg describes endpoints as the core of every clinical trial, since they determine whether a therapy is safe or effective. He notes that AI is not new to imaging and aligns well with pattern recognition, yet its real value lies in identifying details that humans often miss.
Greg stresses that drug development still depends on huge volumes of data spread across legacy systems. Without strong data standardization, AI cannot deliver reliable results. He also points to the FDA’s evolving guidance on AI and emphasizes the need for rigorous validation before using AI-derived measurements for regulatory decisions.
Greg highlights the opportunity to improve efficiency, reduce human burden, and generate more consistent insights. With thoughtful adoption, AI can support better decisions in clinical development and improve outcomes for patients. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Improves Endpoints and Evidence in Clinical Trials]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging &amp; Pathology, Merck Research Laboratories" href="https://soundcloud.com/thebigunlock/gregory-goldmacher-md-associate-vice-president-in-clinical-research-and-head-of-clinical-imaging-pathology-merck-research-laboratories" target="_blank" rel="noreferrer noopener">Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging &amp; Pathology, Merck Research Laboratories</a>
<p>In this episode, Dr. Greg Goldmacher, Associate VP of Clinical Research at Merck, known as MSD outside of the United States and Canada, explains how AI is transforming imaging, clinical trials, and early-stage drug development. Greg describes endpoints as the core of every clinical trial, since they determine whether a therapy is safe or effective. He notes that AI is not new to imaging and aligns well with pattern recognition, yet its real value lies in identifying details that humans often miss.</p>
<p>Greg stresses that drug development still depends on huge volumes of data spread across legacy systems. Without strong data standardization, AI cannot deliver reliable results. He also points to the FDA’s evolving guidance on AI and emphasizes the need for rigorous validation before using AI-derived measurements for regulatory decisions.</p>
<p>Greg highlights the opportunity to improve efficiency, reduce human burden, and generate more consistent insights. With thoughtful adoption, AI can support better decisions in clinical development and improve outcomes for patients. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2292831/c1e-8m44uo13w2a1d92g-kpn7zrjgb81g-xqdomc.mp3" length="30554841"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Gregory Goldmacher, M.D., Associate Vice President in Clinical Research, and Head of Clinical Imaging & Pathology, Merck Research Laboratories
In this episode, Dr. Greg Goldmacher, Associate VP of Clinical Research at Merck, known as MSD outside of the United States and Canada, explains how AI is transforming imaging, clinical trials, and early-stage drug development. Greg describes endpoints as the core of every clinical trial, since they determine whether a therapy is safe or effective. He notes that AI is not new to imaging and aligns well with pattern recognition, yet its real value lies in identifying details that humans often miss.
Greg stresses that drug development still depends on huge volumes of data spread across legacy systems. Without strong data standardization, AI cannot deliver reliable results. He also points to the FDA’s evolving guidance on AI and emphasizes the need for rigorous validation before using AI-derived measurements for regulatory decisions.
Greg highlights the opportunity to improve efficiency, reduce human burden, and generate more consistent insights. With thoughtful adoption, AI can support better decisions in clinical development and improve outcomes for patients. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2292831/c1a-gd22-1p7891xnhjn2-v3rpre.png"></itunes:image>
                                                                            <itunes:duration>00:31:50</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Rural Health Transformation and the Future of Patient-First Care]]>
                </title>
                <pubDate>Fri, 12 Dec 2025 09:17:31 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2285432</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/rural-health-transformation-and-the-future-of-patient-first-care</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Lisa Hunter, Senior Director of Federal Policy &amp; Advocacy, United States of Care" href="https://soundcloud.com/thebigunlock/lisa-hunter-senior-director-of-federal-policy-advocacy-united-states-of-care" target="_blank" rel="noreferrer noopener">Lisa Hunter, Senior Director of Federal Policy &amp; Advocacy, United States of Care</a>
<p>In this episode, Lisa Hunter, Senior Director of Federal Policy and Advocacy at United States of Care, discusses how her organization is working to ensure every American has access to affordable, high-quality care, with a particular focus on rural communities. She explains the new Rural Health Transformation Program—a 50-billion-dollar, five-year federal investment that gives states a rare opportunity to redesign rural health delivery, address workforce gaps, and move toward “patient first care” models that emphasize coordination, whole-person care, and sustainable payment structures.​​</p>
<p>Lisa highlights a growing trust gap around AI in healthcare, noting that patients are more comfortable with AI in back-office and ambient use cases compared to roles that feel like they replace clinicians. She stresses the need for rigorous listening, research, and language that resonates with people, so policy and technology decisions reflect real experiences rather than abstract concepts. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Lisa Hunter, Senior Director of Federal Policy & Advocacy, United States of Care
In this episode, Lisa Hunter, Senior Director of Federal Policy and Advocacy at United States of Care, discusses how her organization is working to ensure every American has access to affordable, high-quality care, with a particular focus on rural communities. She explains the new Rural Health Transformation Program—a 50-billion-dollar, five-year federal investment that gives states a rare opportunity to redesign rural health delivery, address workforce gaps, and move toward “patient first care” models that emphasize coordination, whole-person care, and sustainable payment structures.​​
Lisa highlights a growing trust gap around AI in healthcare, noting that patients are more comfortable with AI in back-office and ambient use cases compared to roles that feel like they replace clinicians. She stresses the need for rigorous listening, research, and language that resonates with people, so policy and technology decisions reflect real experiences rather than abstract concepts. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Rural Health Transformation and the Future of Patient-First Care]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Lisa Hunter, Senior Director of Federal Policy &amp; Advocacy, United States of Care" href="https://soundcloud.com/thebigunlock/lisa-hunter-senior-director-of-federal-policy-advocacy-united-states-of-care" target="_blank" rel="noreferrer noopener">Lisa Hunter, Senior Director of Federal Policy &amp; Advocacy, United States of Care</a>
<p>In this episode, Lisa Hunter, Senior Director of Federal Policy and Advocacy at United States of Care, discusses how her organization is working to ensure every American has access to affordable, high-quality care, with a particular focus on rural communities. She explains the new Rural Health Transformation Program—a 50-billion-dollar, five-year federal investment that gives states a rare opportunity to redesign rural health delivery, address workforce gaps, and move toward “patient first care” models that emphasize coordination, whole-person care, and sustainable payment structures.​​</p>
<p>Lisa highlights a growing trust gap around AI in healthcare, noting that patients are more comfortable with AI in back-office and ambient use cases compared to roles that feel like they replace clinicians. She stresses the need for rigorous listening, research, and language that resonates with people, so policy and technology decisions reflect real experiences rather than abstract concepts. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2285432/c1e-1x00u5pnz0bxvw0q-xxgnjd2qb3zm-bjd4bd.mp3" length="26835201"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Lisa Hunter, Senior Director of Federal Policy & Advocacy, United States of Care
In this episode, Lisa Hunter, Senior Director of Federal Policy and Advocacy at United States of Care, discusses how her organization is working to ensure every American has access to affordable, high-quality care, with a particular focus on rural communities. She explains the new Rural Health Transformation Program—a 50-billion-dollar, five-year federal investment that gives states a rare opportunity to redesign rural health delivery, address workforce gaps, and move toward “patient first care” models that emphasize coordination, whole-person care, and sustainable payment structures.​​
Lisa highlights a growing trust gap around AI in healthcare, noting that patients are more comfortable with AI in back-office and ambient use cases compared to roles that feel like they replace clinicians. She stresses the need for rigorous listening, research, and language that resonates with people, so policy and technology decisions reflect real experiences rather than abstract concepts. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2285432/c1a-gd22-1p79ogdgc4o8-jbqdbg.png"></itunes:image>
                                                                            <itunes:duration>00:27:58</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Solving Healthcare’s Trilemma with Focus, Co-Innovation, and AI]]>
                </title>
                <pubDate>Tue, 09 Dec 2025 07:38:35 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2279885</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/solving-healthcares-trilemma-with-focus-co-innovation-and-ai</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Matthew Blosl, Chief Executive Officer, DexCare" href="https://soundcloud.com/thebigunlock/matthew-blosl-chief-executive-officer-dexcare" target="_blank" rel="noreferrer noopener">Matthew Blosl, Chief Executive Officer, DexCare</a>
<p>In this episode, Matthew Blosl, CEO of DexCare, discusses how he helps high-growth healthcare technology companies navigate critical inflection points by pairing disciplined focus with a culture that embraces failure as a path to innovation. He describes DexCare’s journey from a Providence Health incubated initiative to a scaled care orchestration platform that helps health systems address a “trilemma” of rising patient demand, clinician shortages, and margin pressure.</p>
<p>Matt explains DexCare’s co-innovation model, where every health system becomes an innovation partner rather than a one-size-fits-all implementation, enabled by modern data and AI capabilities. He outlines a pragmatic AI roadmap: first improving internal operations, then enhancing existing products, and finally accelerating true product innovation, while warning that AI can easily drive teams off-mission without strong focus. Matt also points out how fast things are shifting in healthcare and encourages leaders to rethink how they run their organizations and come together more often to tackle the challenges ahead. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Matthew Blosl, Chief Executive Officer, DexCare
In this episode, Matthew Blosl, CEO of DexCare, discusses how he helps high-growth healthcare technology companies navigate critical inflection points by pairing disciplined focus with a culture that embraces failure as a path to innovation. He describes DexCare’s journey from a Providence Health incubated initiative to a scaled care orchestration platform that helps health systems address a “trilemma” of rising patient demand, clinician shortages, and margin pressure.
Matt explains DexCare’s co-innovation model, where every health system becomes an innovation partner rather than a one-size-fits-all implementation, enabled by modern data and AI capabilities. He outlines a pragmatic AI roadmap: first improving internal operations, then enhancing existing products, and finally accelerating true product innovation, while warning that AI can easily drive teams off-mission without strong focus. Matt also points out how fast things are shifting in healthcare and encourages leaders to rethink how they run their organizations and come together more often to tackle the challenges ahead. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Solving Healthcare’s Trilemma with Focus, Co-Innovation, and AI]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Matthew Blosl, Chief Executive Officer, DexCare" href="https://soundcloud.com/thebigunlock/matthew-blosl-chief-executive-officer-dexcare" target="_blank" rel="noreferrer noopener">Matthew Blosl, Chief Executive Officer, DexCare</a>
<p>In this episode, Matthew Blosl, CEO of DexCare, discusses how he helps high-growth healthcare technology companies navigate critical inflection points by pairing disciplined focus with a culture that embraces failure as a path to innovation. He describes DexCare’s journey from a Providence Health incubated initiative to a scaled care orchestration platform that helps health systems address a “trilemma” of rising patient demand, clinician shortages, and margin pressure.</p>
<p>Matt explains DexCare’s co-innovation model, where every health system becomes an innovation partner rather than a one-size-fits-all implementation, enabled by modern data and AI capabilities. He outlines a pragmatic AI roadmap: first improving internal operations, then enhancing existing products, and finally accelerating true product innovation, while warning that AI can easily drive teams off-mission without strong focus. Matt also points out how fast things are shifting in healthcare and encourages leaders to rethink how they run their organizations and come together more often to tackle the challenges ahead. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2279885/c1e-dd66bmqpv6apdj8o-47m0j0w8f39r-062rmb.mp3" length="29916414"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Matthew Blosl, Chief Executive Officer, DexCare
In this episode, Matthew Blosl, CEO of DexCare, discusses how he helps high-growth healthcare technology companies navigate critical inflection points by pairing disciplined focus with a culture that embraces failure as a path to innovation. He describes DexCare’s journey from a Providence Health incubated initiative to a scaled care orchestration platform that helps health systems address a “trilemma” of rising patient demand, clinician shortages, and margin pressure.
Matt explains DexCare’s co-innovation model, where every health system becomes an innovation partner rather than a one-size-fits-all implementation, enabled by modern data and AI capabilities. He outlines a pragmatic AI roadmap: first improving internal operations, then enhancing existing products, and finally accelerating true product innovation, while warning that AI can easily drive teams off-mission without strong focus. Matt also points out how fast things are shifting in healthcare and encourages leaders to rethink how they run their organizations and come together more often to tackle the challenges ahead. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2279885/c1a-gd22-dmx0p9grijr2-gpzjx5.png"></itunes:image>
                                                                            <itunes:duration>00:31:10</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Human Centered Leadership is the Real Unlock for AI in Healthcare]]>
                </title>
                <pubDate>Wed, 03 Dec 2025 09:22:48 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2265598</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/human-centered-leadership-is-the-real-unlock-for-ai-in-healthcare</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/dr-felicia-newhouse-founder-ai-powered-women" title="Dr. Felicia Newhouse, Founder, AI-Powered Women" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Dr. Felicia Newhouse, Founder, AI-Powered Women</a>
<p>In this episode, Dr. Felicia Newhouse, Founder of AI-Powered Women, highlights the need for human centered leadership as the foundation for AI’s future in healthcare. Reflecting on her near-death experience and two decades in tech, she warns that rapid automation may boost efficiency but often leaves people feeling overwhelmed, disconnected, and burned out.</p>
<p>Dr. Newhouse emphasizes that true progress requires qualities only humans can bring, empathy, intuition, emotional intelligence, and what she describes as “systems awareness” and “systems feeling.” These capabilities help leaders understand the broader human impact of digital tools and design AI that supports well-being rather than replacing human judgment.</p>
<p>She urges organizations to slow down, prioritize dignity and belonging, and adopt AI in ways that strengthen human connection. According to Dr. Newhouse, the real unlock for healthcare will come when AI is guided by compassion, humanity, and mindful leadership. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Dr. Felicia Newhouse, Founder, AI-Powered Women
In this episode, Dr. Felicia Newhouse, Founder of AI-Powered Women, highlights the need for human centered leadership as the foundation for AI’s future in healthcare. Reflecting on her near-death experience and two decades in tech, she warns that rapid automation may boost efficiency but often leaves people feeling overwhelmed, disconnected, and burned out.
Dr. Newhouse emphasizes that true progress requires qualities only humans can bring, empathy, intuition, emotional intelligence, and what she describes as “systems awareness” and “systems feeling.” These capabilities help leaders understand the broader human impact of digital tools and design AI that supports well-being rather than replacing human judgment.
She urges organizations to slow down, prioritize dignity and belonging, and adopt AI in ways that strengthen human connection. According to Dr. Newhouse, the real unlock for healthcare will come when AI is guided by compassion, humanity, and mindful leadership. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Human Centered Leadership is the Real Unlock for AI in Healthcare]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/dr-felicia-newhouse-founder-ai-powered-women" title="Dr. Felicia Newhouse, Founder, AI-Powered Women" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Dr. Felicia Newhouse, Founder, AI-Powered Women</a>
<p>In this episode, Dr. Felicia Newhouse, Founder of AI-Powered Women, highlights the need for human centered leadership as the foundation for AI’s future in healthcare. Reflecting on her near-death experience and two decades in tech, she warns that rapid automation may boost efficiency but often leaves people feeling overwhelmed, disconnected, and burned out.</p>
<p>Dr. Newhouse emphasizes that true progress requires qualities only humans can bring, empathy, intuition, emotional intelligence, and what she describes as “systems awareness” and “systems feeling.” These capabilities help leaders understand the broader human impact of digital tools and design AI that supports well-being rather than replacing human judgment.</p>
<p>She urges organizations to slow down, prioritize dignity and belonging, and adopt AI in ways that strengthen human connection. According to Dr. Newhouse, the real unlock for healthcare will come when AI is guided by compassion, humanity, and mindful leadership. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2265598/c1e-xmvvu9wn10sn7og5-v6po2213sk7j-01bbjw.mp3" length="26516196"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Dr. Felicia Newhouse, Founder, AI-Powered Women
In this episode, Dr. Felicia Newhouse, Founder of AI-Powered Women, highlights the need for human centered leadership as the foundation for AI’s future in healthcare. Reflecting on her near-death experience and two decades in tech, she warns that rapid automation may boost efficiency but often leaves people feeling overwhelmed, disconnected, and burned out.
Dr. Newhouse emphasizes that true progress requires qualities only humans can bring, empathy, intuition, emotional intelligence, and what she describes as “systems awareness” and “systems feeling.” These capabilities help leaders understand the broader human impact of digital tools and design AI that supports well-being rather than replacing human judgment.
She urges organizations to slow down, prioritize dignity and belonging, and adopt AI in ways that strengthen human connection. According to Dr. Newhouse, the real unlock for healthcare will come when AI is guided by compassion, humanity, and mindful leadership. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2265598/c1a-gd22-47mjd0jxumk8-v3atro.png"></itunes:image>
                                                                            <itunes:duration>00:27:38</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Virtual-First Care Starts with Making Technology Effortless]]>
                </title>
                <pubDate>Mon, 24 Nov 2025 05:08:10 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2240520</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/virtual-first-care-starts-with-making-technology-effortless</link>
                                <description>
                                            <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare" href="https://soundcloud.com/thebigunlock/chris-gallagher-md-founder-and-chief-strategy-officer-access-telecare" target="_blank" rel="noreferrer noopener">Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare</a>
<p>In this episode, Dr. Chris Gallagher, Founder and Chief Strategy Officer at Access TeleCare, shares valuable insights on the evolution of AI, how virtual care is reshaping access, staffing, and costs across health systems, and why making technology effortless is the key to driving a successful virtual-first care strategy.</p>
<p>Chris recounts the pioneering achievement of building the first virtual ICU in Texas in 2013, which quickly proved life-saving and marked a turning point in virtual health adoption. He discusses how they are addressing physician distribution issues by augmenting in-person staff, shifting its focus from predominantly rural to 70% urban facilities by offering essential 24/7 virtual specialists to care teams. Chris stresses that solutions must be effortless for clinicians, “Fisher Price easy,” so adoption becomes self-perpetuating.</p>
<p>Chris highlights AI’s immense potential to improve efficiency, enhance physician experience, and expedite patient care, especially through automation and a future “virtual-first” healthcare strategy. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[﻿
The Big Unlock · Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare
In this episode, Dr. Chris Gallagher, Founder and Chief Strategy Officer at Access TeleCare, shares valuable insights on the evolution of AI, how virtual care is reshaping access, staffing, and costs across health systems, and why making technology effortless is the key to driving a successful virtual-first care strategy.
Chris recounts the pioneering achievement of building the first virtual ICU in Texas in 2013, which quickly proved life-saving and marked a turning point in virtual health adoption. He discusses how they are addressing physician distribution issues by augmenting in-person staff, shifting its focus from predominantly rural to 70% urban facilities by offering essential 24/7 virtual specialists to care teams. Chris stresses that solutions must be effortless for clinicians, “Fisher Price easy,” so adoption becomes self-perpetuating.
Chris highlights AI’s immense potential to improve efficiency, enhance physician experience, and expedite patient care, especially through automation and a future “virtual-first” healthcare strategy. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Virtual-First Care Starts with Making Technology Effortless]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare" href="https://soundcloud.com/thebigunlock/chris-gallagher-md-founder-and-chief-strategy-officer-access-telecare" target="_blank" rel="noreferrer noopener">Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare</a>
<p>In this episode, Dr. Chris Gallagher, Founder and Chief Strategy Officer at Access TeleCare, shares valuable insights on the evolution of AI, how virtual care is reshaping access, staffing, and costs across health systems, and why making technology effortless is the key to driving a successful virtual-first care strategy.</p>
<p>Chris recounts the pioneering achievement of building the first virtual ICU in Texas in 2013, which quickly proved life-saving and marked a turning point in virtual health adoption. He discusses how they are addressing physician distribution issues by augmenting in-person staff, shifting its focus from predominantly rural to 70% urban facilities by offering essential 24/7 virtual specialists to care teams. Chris stresses that solutions must be effortless for clinicians, “Fisher Price easy,” so adoption becomes self-perpetuating.</p>
<p>Chris highlights AI’s immense potential to improve efficiency, enhance physician experience, and expedite patient care, especially through automation and a future “virtual-first” healthcare strategy. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2240520/c1e-qxrrudmnqot0vkd3-xxg5nwqoi891-obkzeq.mp3" length="23323227"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[﻿
The Big Unlock · Chris Gallagher, M.D., Founder and Chief Strategy Officer, Access TeleCare
In this episode, Dr. Chris Gallagher, Founder and Chief Strategy Officer at Access TeleCare, shares valuable insights on the evolution of AI, how virtual care is reshaping access, staffing, and costs across health systems, and why making technology effortless is the key to driving a successful virtual-first care strategy.
Chris recounts the pioneering achievement of building the first virtual ICU in Texas in 2013, which quickly proved life-saving and marked a turning point in virtual health adoption. He discusses how they are addressing physician distribution issues by augmenting in-person staff, shifting its focus from predominantly rural to 70% urban facilities by offering essential 24/7 virtual specialists to care teams. Chris stresses that solutions must be effortless for clinicians, “Fisher Price easy,” so adoption becomes self-perpetuating.
Chris highlights AI’s immense potential to improve efficiency, enhance physician experience, and expedite patient care, especially through automation and a future “virtual-first” healthcare strategy. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2240520/c1a-gd22-okjd58w2agm8-utgjh6.png"></itunes:image>
                                                                            <itunes:duration>00:24:18</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Technology Must Remain Invisible, Yet Empower Caregivers to Deliver Care Better]]>
                </title>
                <pubDate>Thu, 13 Nov 2025 10:45:10 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2203937</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/technology-must-remain-invisible-yet-empower-caregivers-to-deliver-care-better</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Charles E. Christian, Vice President of Technology and CTO, Franciscan Health" href="https://soundcloud.com/thebigunlock/charles-e-christian-vice-president-of-technology-and-cto-franciscan-health" target="_blank" rel="noreferrer noopener">Charles E. Christian, Vice President of Technology and CTO, Franciscan Health</a>
<p>In this episode, Charles E. Christian, VP of Technology and CTO at Franciscan Health, shares reflections from his five-decade journey in healthcare IT and how Franciscan is blending mission, compassion, and innovation to transform patient care.</p>
<p>Chuck explains how the health system is approaching AI adoption through strong governance and a clear focus on solving real problems, from reducing clinician burden to enhancing care delivery. He highlights several key initiatives, including voice agent pilots that help physicians reclaim after-hours time, a Tech Innovation Lab that allows teams to safely experiment and “fail fast,” and a virtual nurse mentoring program that connects senior nurses with new graduates for real-time guidance.</p>
<p>Chuck states that technology should serve, not distract, and the true goal of digital transformation is to enable better care for people. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Charles E. Christian, Vice President of Technology and CTO, Franciscan Health
In this episode, Charles E. Christian, VP of Technology and CTO at Franciscan Health, shares reflections from his five-decade journey in healthcare IT and how Franciscan is blending mission, compassion, and innovation to transform patient care.
Chuck explains how the health system is approaching AI adoption through strong governance and a clear focus on solving real problems, from reducing clinician burden to enhancing care delivery. He highlights several key initiatives, including voice agent pilots that help physicians reclaim after-hours time, a Tech Innovation Lab that allows teams to safely experiment and “fail fast,” and a virtual nurse mentoring program that connects senior nurses with new graduates for real-time guidance.
Chuck states that technology should serve, not distract, and the true goal of digital transformation is to enable better care for people. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Technology Must Remain Invisible, Yet Empower Caregivers to Deliver Care Better]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Charles E. Christian, Vice President of Technology and CTO, Franciscan Health" href="https://soundcloud.com/thebigunlock/charles-e-christian-vice-president-of-technology-and-cto-franciscan-health" target="_blank" rel="noreferrer noopener">Charles E. Christian, Vice President of Technology and CTO, Franciscan Health</a>
<p>In this episode, Charles E. Christian, VP of Technology and CTO at Franciscan Health, shares reflections from his five-decade journey in healthcare IT and how Franciscan is blending mission, compassion, and innovation to transform patient care.</p>
<p>Chuck explains how the health system is approaching AI adoption through strong governance and a clear focus on solving real problems, from reducing clinician burden to enhancing care delivery. He highlights several key initiatives, including voice agent pilots that help physicians reclaim after-hours time, a Tech Innovation Lab that allows teams to safely experiment and “fail fast,” and a virtual nurse mentoring program that connects senior nurses with new graduates for real-time guidance.</p>
<p>Chuck states that technology should serve, not distract, and the true goal of digital transformation is to enable better care for people. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2203937/c1e-wnzzb36o3pu0g6q2-dmxm0v0ksvmq-upkejp.mp3" length="30011907"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Charles E. Christian, Vice President of Technology and CTO, Franciscan Health
In this episode, Charles E. Christian, VP of Technology and CTO at Franciscan Health, shares reflections from his five-decade journey in healthcare IT and how Franciscan is blending mission, compassion, and innovation to transform patient care.
Chuck explains how the health system is approaching AI adoption through strong governance and a clear focus on solving real problems, from reducing clinician burden to enhancing care delivery. He highlights several key initiatives, including voice agent pilots that help physicians reclaim after-hours time, a Tech Innovation Lab that allows teams to safely experiment and “fail fast,” and a virtual nurse mentoring program that connects senior nurses with new graduates for real-time guidance.
Chuck states that technology should serve, not distract, and the true goal of digital transformation is to enable better care for people. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2203937/c1a-gd22-gp9pqk92i6zx-qk0ph5.png"></itunes:image>
                                                                            <itunes:duration>00:31:16</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Empowering Patients and Closing Health Gaps with AI and Connected Care]]>
                </title>
                <pubDate>Tue, 04 Nov 2025 05:52:52 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
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                                    <link>https://the-big-unlock.castos.com/episodes/empowering-patients-and-closing-health-gaps-with-ai-and-connected-care</link>
                                <description>
                                            <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Anil Saldanha, Chief Innovation Officer, Rush University System for Health" href="https://soundcloud.com/thebigunlock/anil-saldanha-chief-innovation-officer-rush-university-system-for-health" target="_blank" rel="noreferrer noopener">Anil Saldanha, Chief Innovation Officer, Rush University System for Health</a>
<p>In this episode, Anil Saldanha, Chief Innovation Officer at Rush University System for Health shares how Rush is addressing deep-rooted health inequities in Chicago by targeting the life expectancy gap through bold, system-wide interventions.</p>
<p>Anil highlights Rush’s commitment to public health, chronic disease management, and early cancer detection by referring to innovative initiatives like Rush Connect Plus, which is an on-demand, subscription-based virtual care model, and the rollout of Grail’s multi-cancer early detection test. He explains their use of cutting-edge AI technologies, from ambient listening and AI-powered symptom checkers to novel behavioral health kiosks leveraging multi-agent generative AI for PTSD care.</p>
<p>Anil points to the impact of consumer-driven digital tools, health equity analytics, and a data warehouse that will enable targeted interventions for chronic care. He closes with optimism about AI’s future in healthcare, the shift toward “connected care anywhere,” and the growing role of empowered, informed patients. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[﻿
The Big Unlock · Anil Saldanha, Chief Innovation Officer, Rush University System for Health
In this episode, Anil Saldanha, Chief Innovation Officer at Rush University System for Health shares how Rush is addressing deep-rooted health inequities in Chicago by targeting the life expectancy gap through bold, system-wide interventions.
Anil highlights Rush’s commitment to public health, chronic disease management, and early cancer detection by referring to innovative initiatives like Rush Connect Plus, which is an on-demand, subscription-based virtual care model, and the rollout of Grail’s multi-cancer early detection test. He explains their use of cutting-edge AI technologies, from ambient listening and AI-powered symptom checkers to novel behavioral health kiosks leveraging multi-agent generative AI for PTSD care.
Anil points to the impact of consumer-driven digital tools, health equity analytics, and a data warehouse that will enable targeted interventions for chronic care. He closes with optimism about AI’s future in healthcare, the shift toward “connected care anywhere,” and the growing role of empowered, informed patients. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Empowering Patients and Closing Health Gaps with AI and Connected Care]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Anil Saldanha, Chief Innovation Officer, Rush University System for Health" href="https://soundcloud.com/thebigunlock/anil-saldanha-chief-innovation-officer-rush-university-system-for-health" target="_blank" rel="noreferrer noopener">Anil Saldanha, Chief Innovation Officer, Rush University System for Health</a>
<p>In this episode, Anil Saldanha, Chief Innovation Officer at Rush University System for Health shares how Rush is addressing deep-rooted health inequities in Chicago by targeting the life expectancy gap through bold, system-wide interventions.</p>
<p>Anil highlights Rush’s commitment to public health, chronic disease management, and early cancer detection by referring to innovative initiatives like Rush Connect Plus, which is an on-demand, subscription-based virtual care model, and the rollout of Grail’s multi-cancer early detection test. He explains their use of cutting-edge AI technologies, from ambient listening and AI-powered symptom checkers to novel behavioral health kiosks leveraging multi-agent generative AI for PTSD care.</p>
<p>Anil points to the impact of consumer-driven digital tools, health equity analytics, and a data warehouse that will enable targeted interventions for chronic care. He closes with optimism about AI’s future in healthcare, the shift toward “connected care anywhere,” and the growing role of empowered, informed patients. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2185003/c1e-9255bdr367adv817-kpno1191tzwp-qab6bg.mp3" length="33300369"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[﻿
The Big Unlock · Anil Saldanha, Chief Innovation Officer, Rush University System for Health
In this episode, Anil Saldanha, Chief Innovation Officer at Rush University System for Health shares how Rush is addressing deep-rooted health inequities in Chicago by targeting the life expectancy gap through bold, system-wide interventions.
Anil highlights Rush’s commitment to public health, chronic disease management, and early cancer detection by referring to innovative initiatives like Rush Connect Plus, which is an on-demand, subscription-based virtual care model, and the rollout of Grail’s multi-cancer early detection test. He explains their use of cutting-edge AI technologies, from ambient listening and AI-powered symptom checkers to novel behavioral health kiosks leveraging multi-agent generative AI for PTSD care.
Anil points to the impact of consumer-driven digital tools, health equity analytics, and a data warehouse that will enable targeted interventions for chronic care. He closes with optimism about AI’s future in healthcare, the shift toward “connected care anywhere,” and the growing role of empowered, informed patients. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2185003/c1a-gd22-0v70qqz0urdx-2x3xim.png"></itunes:image>
                                                                            <itunes:duration>00:34:42</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Advancing Pediatric Care with AI in Radiology and Virtual Trials]]>
                </title>
                <pubDate>Thu, 23 Oct 2025 07:54:16 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2170398</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/advancing-pediatric-care-with-ai-in-radiology-and-virtual-trials</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/paul-yi-md-associate-member-in-radiology-section-chief-of-intelligent-imaging-informatics-i3-st-jude-childrens-research-hospital" title="Paul Yi, MD, Associate Member in Radiology, Section Chief of Intelligent Imaging Informatics (I3), St. Jude Children's Research Hospital" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Paul Yi, MD, Associate Member in Radiology, Section Chief of Intelligent Imaging Informatics (I3), St. Jude Children's Research Hospital</a>
<p>In this episode, Dr. Paul Yi, Associate Member, Department of Radiology, Section Chief of Intelligent Imaging Informatics (I3) at St. Jude Children’s Research Hospital, shares his journey from radiology training at Johns Hopkins to leading AI initiatives at St. Jude, focusing on pediatric cancer and other catastrophic diseases. </p>
<p>Dr. Yi highlights how AI is transforming the radiology workflow, from automating imaging protocols and improving image reconstruction to translating complex medical reports into patient-friendly language. He emphasizes the importance of data strategy, discussing the integration of clinical EMRs, PACS, and research databases, ensuring interoperability while leveraging domain expertise across disciplines. He explores generative AI applications, including virtual imaging trials that simulate patient populations for safer, faster, and cost-effective clinical research, as well as patient-facing applications like AI chatbots for healthcare education, noting both potential and limitations in trust and accuracy.</p>
<p>Dr. Yi reflects on bridging research and commercialization, underscoring the need to align academic and industry incentives. He envisions a future powered by multimodal AI models that combine imaging, vitals, labs, and clinical text to deliver comprehensive, personalized insights – accelerating precision care and innovation in pediatric oncology. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Paul Yi, MD, Associate Member in Radiology, Section Chief of Intelligent Imaging Informatics (I3), St. Jude Children's Research Hospital
In this episode, Dr. Paul Yi, Associate Member, Department of Radiology, Section Chief of Intelligent Imaging Informatics (I3) at St. Jude Children’s Research Hospital, shares his journey from radiology training at Johns Hopkins to leading AI initiatives at St. Jude, focusing on pediatric cancer and other catastrophic diseases. 
Dr. Yi highlights how AI is transforming the radiology workflow, from automating imaging protocols and improving image reconstruction to translating complex medical reports into patient-friendly language. He emphasizes the importance of data strategy, discussing the integration of clinical EMRs, PACS, and research databases, ensuring interoperability while leveraging domain expertise across disciplines. He explores generative AI applications, including virtual imaging trials that simulate patient populations for safer, faster, and cost-effective clinical research, as well as patient-facing applications like AI chatbots for healthcare education, noting both potential and limitations in trust and accuracy.
Dr. Yi reflects on bridging research and commercialization, underscoring the need to align academic and industry incentives. He envisions a future powered by multimodal AI models that combine imaging, vitals, labs, and clinical text to deliver comprehensive, personalized insights – accelerating precision care and innovation in pediatric oncology. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Advancing Pediatric Care with AI in Radiology and Virtual Trials]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/paul-yi-md-associate-member-in-radiology-section-chief-of-intelligent-imaging-informatics-i3-st-jude-childrens-research-hospital" title="Paul Yi, MD, Associate Member in Radiology, Section Chief of Intelligent Imaging Informatics (I3), St. Jude Children's Research Hospital" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Paul Yi, MD, Associate Member in Radiology, Section Chief of Intelligent Imaging Informatics (I3), St. Jude Children's Research Hospital</a>
<p>In this episode, Dr. Paul Yi, Associate Member, Department of Radiology, Section Chief of Intelligent Imaging Informatics (I3) at St. Jude Children’s Research Hospital, shares his journey from radiology training at Johns Hopkins to leading AI initiatives at St. Jude, focusing on pediatric cancer and other catastrophic diseases. </p>
<p>Dr. Yi highlights how AI is transforming the radiology workflow, from automating imaging protocols and improving image reconstruction to translating complex medical reports into patient-friendly language. He emphasizes the importance of data strategy, discussing the integration of clinical EMRs, PACS, and research databases, ensuring interoperability while leveraging domain expertise across disciplines. He explores generative AI applications, including virtual imaging trials that simulate patient populations for safer, faster, and cost-effective clinical research, as well as patient-facing applications like AI chatbots for healthcare education, noting both potential and limitations in trust and accuracy.</p>
<p>Dr. Yi reflects on bridging research and commercialization, underscoring the need to align academic and industry incentives. He envisions a future powered by multimodal AI models that combine imaging, vitals, labs, and clinical text to deliver comprehensive, personalized insights – accelerating precision care and innovation in pediatric oncology. Take a listen.</p>]]>
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                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Paul Yi, MD, Associate Member in Radiology, Section Chief of Intelligent Imaging Informatics (I3), St. Jude Children's Research Hospital
In this episode, Dr. Paul Yi, Associate Member, Department of Radiology, Section Chief of Intelligent Imaging Informatics (I3) at St. Jude Children’s Research Hospital, shares his journey from radiology training at Johns Hopkins to leading AI initiatives at St. Jude, focusing on pediatric cancer and other catastrophic diseases. 
Dr. Yi highlights how AI is transforming the radiology workflow, from automating imaging protocols and improving image reconstruction to translating complex medical reports into patient-friendly language. He emphasizes the importance of data strategy, discussing the integration of clinical EMRs, PACS, and research databases, ensuring interoperability while leveraging domain expertise across disciplines. He explores generative AI applications, including virtual imaging trials that simulate patient populations for safer, faster, and cost-effective clinical research, as well as patient-facing applications like AI chatbots for healthcare education, noting both potential and limitations in trust and accuracy.
Dr. Yi reflects on bridging research and commercialization, underscoring the need to align academic and industry incentives. He envisions a future powered by multimodal AI models that combine imaging, vitals, labs, and clinical text to deliver comprehensive, personalized insights – accelerating precision care and innovation in pediatric oncology. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2170398/c1a-gd22-jpn3vjpruq56-cbzicm.png"></itunes:image>
                                                                            <itunes:duration>00:29:10</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Transforming Behavioral Health by Merging Psychology with AI]]>
                </title>
                <pubDate>Thu, 16 Oct 2025 10:45:30 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
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                                    <link>https://the-big-unlock.castos.com/episodes/transforming-behavioural-health-by-merging-psychology-with-ai</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Andreas Michaelides, Shaping Clinical AI with Google, Ex-Noom Chief of Psychology" href="https://soundcloud.com/thebigunlock/dr-andreas-michaelides-shaping-clinical-ai-with-google-ex-noom-chief-of-psychology" target="_blank" rel="noreferrer noopener">Dr. Andreas Michaelides, Shaping Clinical AI with Google, Ex-Noom Chief of Psychology</a>
<p>In this episode, Dr. Andreas Michaelides, Clinical Psychologist helping shape Clinical AI with Google and Former Chief of Psychology at Noom, discusses the evolving intersection of technology and psychology, emphasizing how digital platforms and behavioral science can drive meaningful health outcomes at scale.</p>
<p>Drawing from his extensive experience at Noom and current role at Google, he highlights the value of integrating personalized care, education, and accountability through innovative technologies such as AI and wearables. Dr. Michaelides explores the ethical complexities and societal impact of AI-driven health solutions, underscoring the necessity for thoughtful governance and responsible implementation. He notes the transformative potential of predictive analytics and adaptive digital tools in enabling better assessments, interventions, and relationships between humans and technology.</p>
<p>Dr. Michaelides encourages practitioners to embrace uncertainty, unlearn traditional paradigms, and innovate by merging expertise with curiosity. While acknowledging fears around the rapid pace of tech advancement, he conveys an optimistic outlook on the future of digital health and behavioral change. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Dr. Andreas Michaelides, Shaping Clinical AI with Google, Ex-Noom Chief of Psychology
In this episode, Dr. Andreas Michaelides, Clinical Psychologist helping shape Clinical AI with Google and Former Chief of Psychology at Noom, discusses the evolving intersection of technology and psychology, emphasizing how digital platforms and behavioral science can drive meaningful health outcomes at scale.
Drawing from his extensive experience at Noom and current role at Google, he highlights the value of integrating personalized care, education, and accountability through innovative technologies such as AI and wearables. Dr. Michaelides explores the ethical complexities and societal impact of AI-driven health solutions, underscoring the necessity for thoughtful governance and responsible implementation. He notes the transformative potential of predictive analytics and adaptive digital tools in enabling better assessments, interventions, and relationships between humans and technology.
Dr. Michaelides encourages practitioners to embrace uncertainty, unlearn traditional paradigms, and innovate by merging expertise with curiosity. While acknowledging fears around the rapid pace of tech advancement, he conveys an optimistic outlook on the future of digital health and behavioral change. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Transforming Behavioral Health by Merging Psychology with AI]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Andreas Michaelides, Shaping Clinical AI with Google, Ex-Noom Chief of Psychology" href="https://soundcloud.com/thebigunlock/dr-andreas-michaelides-shaping-clinical-ai-with-google-ex-noom-chief-of-psychology" target="_blank" rel="noreferrer noopener">Dr. Andreas Michaelides, Shaping Clinical AI with Google, Ex-Noom Chief of Psychology</a>
<p>In this episode, Dr. Andreas Michaelides, Clinical Psychologist helping shape Clinical AI with Google and Former Chief of Psychology at Noom, discusses the evolving intersection of technology and psychology, emphasizing how digital platforms and behavioral science can drive meaningful health outcomes at scale.</p>
<p>Drawing from his extensive experience at Noom and current role at Google, he highlights the value of integrating personalized care, education, and accountability through innovative technologies such as AI and wearables. Dr. Michaelides explores the ethical complexities and societal impact of AI-driven health solutions, underscoring the necessity for thoughtful governance and responsible implementation. He notes the transformative potential of predictive analytics and adaptive digital tools in enabling better assessments, interventions, and relationships between humans and technology.</p>
<p>Dr. Michaelides encourages practitioners to embrace uncertainty, unlearn traditional paradigms, and innovate by merging expertise with curiosity. While acknowledging fears around the rapid pace of tech advancement, he conveys an optimistic outlook on the future of digital health and behavioral change. Take a listen.</p>]]>
                </content:encoded>
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                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Dr. Andreas Michaelides, Shaping Clinical AI with Google, Ex-Noom Chief of Psychology
In this episode, Dr. Andreas Michaelides, Clinical Psychologist helping shape Clinical AI with Google and Former Chief of Psychology at Noom, discusses the evolving intersection of technology and psychology, emphasizing how digital platforms and behavioral science can drive meaningful health outcomes at scale.
Drawing from his extensive experience at Noom and current role at Google, he highlights the value of integrating personalized care, education, and accountability through innovative technologies such as AI and wearables. Dr. Michaelides explores the ethical complexities and societal impact of AI-driven health solutions, underscoring the necessity for thoughtful governance and responsible implementation. He notes the transformative potential of predictive analytics and adaptive digital tools in enabling better assessments, interventions, and relationships between humans and technology.
Dr. Michaelides encourages practitioners to embrace uncertainty, unlearn traditional paradigms, and innovate by merging expertise with curiosity. While acknowledging fears around the rapid pace of tech advancement, he conveys an optimistic outlook on the future of digital health and behavioral change. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2166316/c1a-gd22-mkwjoggrfpj-09sd6s.png"></itunes:image>
                                                                            <itunes:duration>00:21:28</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Bridging the AI Gap in Healthcare with AI Literacy and Trust]]>
                </title>
                <pubDate>Mon, 06 Oct 2025 05:52:20 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
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                                    <link>https://the-big-unlock.castos.com/episodes/bridging-the-ai-gap-in-healthcare-with-ai-literacy-and-trust</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/jan-beger-global-head-of-ai-advocacy-ge-healthcare" title="Jan Beger, Global Head of AI Advocacy, GE Healthcare" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Jan Beger, Global Head of AI Advocacy, GE Healthcare</a>
<p>In this episode, Jan Beger, Global Head of AI Advocacy at GE Healthcare, shares his mission to bridge the gap between the conceptual promise and real-world impact of AI in healthcare. He stresses on the critical need to build AI literacy and trust among clinicians, executives, and students, and explains why a human-centric approach and strong change management are critical for successful adoption.</p>
<p>Jan highlights GE’s global AI literacy programs that train employees and clinicians on responsible use, practical applications, and critical evaluation of AI. He highlights how moving beyond pilots to strategic, systemwide deployment requires continuous education, executive engagement, and a focus on change management. He also spoke about GE’s successes such as improved efficiency in software development and innovations like AI-guided handheld ultrasound devices that democratize imaging by supporting users of varied expertise, as well as the challenges of keeping AI tools robust and up-to-date.</p>
<p>Jan addresses the future of the workforce, noting that adaptability and tech fluency will be essential as 70% of job skills evolve by 2030. He encourages healthcare leaders to see AI not just as technology, but as a transformative tool to enhance care and outcomes. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Jan Beger, Global Head of AI Advocacy, GE Healthcare
In this episode, Jan Beger, Global Head of AI Advocacy at GE Healthcare, shares his mission to bridge the gap between the conceptual promise and real-world impact of AI in healthcare. He stresses on the critical need to build AI literacy and trust among clinicians, executives, and students, and explains why a human-centric approach and strong change management are critical for successful adoption.
Jan highlights GE’s global AI literacy programs that train employees and clinicians on responsible use, practical applications, and critical evaluation of AI. He highlights how moving beyond pilots to strategic, systemwide deployment requires continuous education, executive engagement, and a focus on change management. He also spoke about GE’s successes such as improved efficiency in software development and innovations like AI-guided handheld ultrasound devices that democratize imaging by supporting users of varied expertise, as well as the challenges of keeping AI tools robust and up-to-date.
Jan addresses the future of the workforce, noting that adaptability and tech fluency will be essential as 70% of job skills evolve by 2030. He encourages healthcare leaders to see AI not just as technology, but as a transformative tool to enhance care and outcomes. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Bridging the AI Gap in Healthcare with AI Literacy and Trust]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/jan-beger-global-head-of-ai-advocacy-ge-healthcare" title="Jan Beger, Global Head of AI Advocacy, GE Healthcare" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Jan Beger, Global Head of AI Advocacy, GE Healthcare</a>
<p>In this episode, Jan Beger, Global Head of AI Advocacy at GE Healthcare, shares his mission to bridge the gap between the conceptual promise and real-world impact of AI in healthcare. He stresses on the critical need to build AI literacy and trust among clinicians, executives, and students, and explains why a human-centric approach and strong change management are critical for successful adoption.</p>
<p>Jan highlights GE’s global AI literacy programs that train employees and clinicians on responsible use, practical applications, and critical evaluation of AI. He highlights how moving beyond pilots to strategic, systemwide deployment requires continuous education, executive engagement, and a focus on change management. He also spoke about GE’s successes such as improved efficiency in software development and innovations like AI-guided handheld ultrasound devices that democratize imaging by supporting users of varied expertise, as well as the challenges of keeping AI tools robust and up-to-date.</p>
<p>Jan addresses the future of the workforce, noting that adaptability and tech fluency will be essential as 70% of job skills evolve by 2030. He encourages healthcare leaders to see AI not just as technology, but as a transformative tool to enhance care and outcomes. Take a listen.</p>]]>
                </content:encoded>
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                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Jan Beger, Global Head of AI Advocacy, GE Healthcare
In this episode, Jan Beger, Global Head of AI Advocacy at GE Healthcare, shares his mission to bridge the gap between the conceptual promise and real-world impact of AI in healthcare. He stresses on the critical need to build AI literacy and trust among clinicians, executives, and students, and explains why a human-centric approach and strong change management are critical for successful adoption.
Jan highlights GE’s global AI literacy programs that train employees and clinicians on responsible use, practical applications, and critical evaluation of AI. He highlights how moving beyond pilots to strategic, systemwide deployment requires continuous education, executive engagement, and a focus on change management. He also spoke about GE’s successes such as improved efficiency in software development and innovations like AI-guided handheld ultrasound devices that democratize imaging by supporting users of varied expertise, as well as the challenges of keeping AI tools robust and up-to-date.
Jan addresses the future of the workforce, noting that adaptability and tech fluency will be essential as 70% of job skills evolve by 2030. He encourages healthcare leaders to see AI not just as technology, but as a transformative tool to enhance care and outcomes. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2158720/c1a-gd22-v6p104mdip15-wutvrs.png"></itunes:image>
                                                                            <itunes:duration>00:25:37</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI Innovation Across Healthcare and Pharma]]>
                </title>
                <pubDate>Tue, 23 Sep 2025 10:12:23 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
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                                    <link>https://the-big-unlock.castos.com/episodes/ai-innovation-across-healthcare-and-pharma</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/thomas-fuchs-chief-ai-officer-eli-lilly-and-company" title="Thomas Fuchs, Chief AI Officer, Eli Lilly and Company" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Thomas Fuchs, Chief AI Officer, Eli Lilly and Company</a>
<p>In this episode, Thomas Fuchs, Chief AI Officer at Eli Lilly, shares his journey from early machine learning research to spearheading transformative AI initiatives across the pharmaceutical value chain. Lilly is running over a thousand AI projects—from drug discovery and development to manufacturing and commercial operations—leveraging innovations like language models for chatbots, computer vision for quality control, and biomarker development.</p>
<p>Thomas emphasizes trust, transparency, and collaboration as critical to AI adoption, supported by AI certification programs for all Lilly technology employees, as well as AI education resources being made available for everyone at Lilly. He also highlights the company’s unique “lab-in-the-loop” setups that generate synthetic data to accelerate innovation.</p>
<p>Thomas shares real-world successes, including AI-assisted drug discovery and intelligent chatbots, and how AI is building confidence across the organization. With robust data infrastructure and scalable strategies for synthesizing large datasets, Lilly is driving rapid innovation. Thomas predicts faster drug design, broader access to medicines, and continuous education as defining trends for AI in healthcare. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Thomas Fuchs, Chief AI Officer, Eli Lilly and Company
In this episode, Thomas Fuchs, Chief AI Officer at Eli Lilly, shares his journey from early machine learning research to spearheading transformative AI initiatives across the pharmaceutical value chain. Lilly is running over a thousand AI projects—from drug discovery and development to manufacturing and commercial operations—leveraging innovations like language models for chatbots, computer vision for quality control, and biomarker development.
Thomas emphasizes trust, transparency, and collaboration as critical to AI adoption, supported by AI certification programs for all Lilly technology employees, as well as AI education resources being made available for everyone at Lilly. He also highlights the company’s unique “lab-in-the-loop” setups that generate synthetic data to accelerate innovation.
Thomas shares real-world successes, including AI-assisted drug discovery and intelligent chatbots, and how AI is building confidence across the organization. With robust data infrastructure and scalable strategies for synthesizing large datasets, Lilly is driving rapid innovation. Thomas predicts faster drug design, broader access to medicines, and continuous education as defining trends for AI in healthcare. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI Innovation Across Healthcare and Pharma]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
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                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/thomas-fuchs-chief-ai-officer-eli-lilly-and-company" title="Thomas Fuchs, Chief AI Officer, Eli Lilly and Company" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Thomas Fuchs, Chief AI Officer, Eli Lilly and Company</a>
<p>In this episode, Thomas Fuchs, Chief AI Officer at Eli Lilly, shares his journey from early machine learning research to spearheading transformative AI initiatives across the pharmaceutical value chain. Lilly is running over a thousand AI projects—from drug discovery and development to manufacturing and commercial operations—leveraging innovations like language models for chatbots, computer vision for quality control, and biomarker development.</p>
<p>Thomas emphasizes trust, transparency, and collaboration as critical to AI adoption, supported by AI certification programs for all Lilly technology employees, as well as AI education resources being made available for everyone at Lilly. He also highlights the company’s unique “lab-in-the-loop” setups that generate synthetic data to accelerate innovation.</p>
<p>Thomas shares real-world successes, including AI-assisted drug discovery and intelligent chatbots, and how AI is building confidence across the organization. With robust data infrastructure and scalable strategies for synthesizing large datasets, Lilly is driving rapid innovation. Thomas predicts faster drug design, broader access to medicines, and continuous education as defining trends for AI in healthcare. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2147347/c1e-60ddiojqgvsndw39-rk38oj4jfxz0-pduesz.mp3" length="26404440"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Thomas Fuchs, Chief AI Officer, Eli Lilly and Company
In this episode, Thomas Fuchs, Chief AI Officer at Eli Lilly, shares his journey from early machine learning research to spearheading transformative AI initiatives across the pharmaceutical value chain. Lilly is running over a thousand AI projects—from drug discovery and development to manufacturing and commercial operations—leveraging innovations like language models for chatbots, computer vision for quality control, and biomarker development.
Thomas emphasizes trust, transparency, and collaboration as critical to AI adoption, supported by AI certification programs for all Lilly technology employees, as well as AI education resources being made available for everyone at Lilly. He also highlights the company’s unique “lab-in-the-loop” setups that generate synthetic data to accelerate innovation.
Thomas shares real-world successes, including AI-assisted drug discovery and intelligent chatbots, and how AI is building confidence across the organization. With robust data infrastructure and scalable strategies for synthesizing large datasets, Lilly is driving rapid innovation. Thomas predicts faster drug design, broader access to medicines, and continuous education as defining trends for AI in healthcare. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2147347/c1a-gd22-okz16mv4i59o-oahamd.png"></itunes:image>
                                                                            <itunes:duration>00:27:36</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI in Healthcare is an Arbitrage of Knowledge for Time]]>
                </title>
                <pubDate>Mon, 15 Sep 2025 05:49:25 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2141010</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-in-healthcare-is-an-arbitrage-of-knowledge-for-time</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/dr-girish-n-nadkarni-chief-ai-officer-mount-sinai-health-system" title="Dr. Girish N. Nadkarni, Chief AI Officer, Mount Sinai Health System" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Dr. Girish N. Nadkarni, Chief AI Officer, Mount Sinai Health System</a>
<p>In this episode, Dr. Girish N. Nadkarni, Chief AI Officer at Mount Sinai Health System, discusses his background as a physician-technologist and his vision for AI in healthcare as a tool that augments rather than replaces clinicians.</p>
<p>Dr. Nadkarni shares insights on how AI is reshaping healthcare. He describes AI as an <em>‘arbitrage of knowledge for time,</em>’ enabling physicians to spend less time on administrative work and more time with patients. He also shares real-world examples including ambient AI scribes that eliminate manual note-taking and predictive models that detect patient deterioration hours before it occurs, especially in critical care units such as the NICU. Dr. Nadkarni distinguishes predictive AI’s deterministic approach from generative AI’s flexible, non-linear potential, emphasizing the need for governance, ethics, and trust in deploying both. He outlines Mount Sinai’s cross-functional framework—spanning care, operations, workforce, and research—supported by an assurance lab to monitor bias and safety.</p>
<p>Dr. Girish highlights current AI applications that save physicians time and enable proactive care, while predicting future developments will include multimodal integration of text, voice, images, and video to better reflect clinical decision-making processes. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Dr. Girish N. Nadkarni, Chief AI Officer, Mount Sinai Health System
In this episode, Dr. Girish N. Nadkarni, Chief AI Officer at Mount Sinai Health System, discusses his background as a physician-technologist and his vision for AI in healthcare as a tool that augments rather than replaces clinicians.
Dr. Nadkarni shares insights on how AI is reshaping healthcare. He describes AI as an ‘arbitrage of knowledge for time,’ enabling physicians to spend less time on administrative work and more time with patients. He also shares real-world examples including ambient AI scribes that eliminate manual note-taking and predictive models that detect patient deterioration hours before it occurs, especially in critical care units such as the NICU. Dr. Nadkarni distinguishes predictive AI’s deterministic approach from generative AI’s flexible, non-linear potential, emphasizing the need for governance, ethics, and trust in deploying both. He outlines Mount Sinai’s cross-functional framework—spanning care, operations, workforce, and research—supported by an assurance lab to monitor bias and safety.
Dr. Girish highlights current AI applications that save physicians time and enable proactive care, while predicting future developments will include multimodal integration of text, voice, images, and video to better reflect clinical decision-making processes. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI in Healthcare is an Arbitrage of Knowledge for Time]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/dr-girish-n-nadkarni-chief-ai-officer-mount-sinai-health-system" title="Dr. Girish N. Nadkarni, Chief AI Officer, Mount Sinai Health System" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Dr. Girish N. Nadkarni, Chief AI Officer, Mount Sinai Health System</a>
<p>In this episode, Dr. Girish N. Nadkarni, Chief AI Officer at Mount Sinai Health System, discusses his background as a physician-technologist and his vision for AI in healthcare as a tool that augments rather than replaces clinicians.</p>
<p>Dr. Nadkarni shares insights on how AI is reshaping healthcare. He describes AI as an <em>‘arbitrage of knowledge for time,</em>’ enabling physicians to spend less time on administrative work and more time with patients. He also shares real-world examples including ambient AI scribes that eliminate manual note-taking and predictive models that detect patient deterioration hours before it occurs, especially in critical care units such as the NICU. Dr. Nadkarni distinguishes predictive AI’s deterministic approach from generative AI’s flexible, non-linear potential, emphasizing the need for governance, ethics, and trust in deploying both. He outlines Mount Sinai’s cross-functional framework—spanning care, operations, workforce, and research—supported by an assurance lab to monitor bias and safety.</p>
<p>Dr. Girish highlights current AI applications that save physicians time and enable proactive care, while predicting future developments will include multimodal integration of text, voice, images, and video to better reflect clinical decision-making processes. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2141010/c1e-dd66bm3gwdbpdj8o-qdo9gj5mt6zk-la7yzx.mp3" length="25845660"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Dr. Girish N. Nadkarni, Chief AI Officer, Mount Sinai Health System
In this episode, Dr. Girish N. Nadkarni, Chief AI Officer at Mount Sinai Health System, discusses his background as a physician-technologist and his vision for AI in healthcare as a tool that augments rather than replaces clinicians.
Dr. Nadkarni shares insights on how AI is reshaping healthcare. He describes AI as an ‘arbitrage of knowledge for time,’ enabling physicians to spend less time on administrative work and more time with patients. He also shares real-world examples including ambient AI scribes that eliminate manual note-taking and predictive models that detect patient deterioration hours before it occurs, especially in critical care units such as the NICU. Dr. Nadkarni distinguishes predictive AI’s deterministic approach from generative AI’s flexible, non-linear potential, emphasizing the need for governance, ethics, and trust in deploying both. He outlines Mount Sinai’s cross-functional framework—spanning care, operations, workforce, and research—supported by an assurance lab to monitor bias and safety.
Dr. Girish highlights current AI applications that save physicians time and enable proactive care, while predicting future developments will include multimodal integration of text, voice, images, and video to better reflect clinical decision-making processes. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2141010/c1a-gd22-kp9716dvf1n-xjzfcr.png"></itunes:image>
                                                                            <itunes:duration>00:26:56</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI, Design, and the Future of Operational Workflows in Unlocking Healthcare Efficiency]]>
                </title>
                <pubDate>Mon, 08 Sep 2025 07:03:59 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2135488</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-design-and-the-future-of-operational-workflows-in-unlocking-healthcare-efficiency</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/michael-docktor-md-co-founder-and-ceo-of-dock-health" title="Michael Docktor, MD, Co-founder and CEO of Dock Health" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Michael Docktor, MD, Co-founder and CEO of Dock Health</a>
<p>In this episode, Dr. Michael Docktor, Co-founder and CEO at Dock Health, shares his journey from being a pediatric gastroenterologist at Boston Children’s Hospital to building a healthcare technology company. Inspired by his sister’s medical experiences and his family’s design background, Dr. Doctor combined medicine, design, and technology to address inefficiencies in operational workflows, particularly the administrative burdens that weigh heavily on providers and staff.</p>
<p>Dr. Docktor explains how Dock Health was created to serve as a productivity platform for healthcare, filling the gap between electronic health records (EHRs) and the countless administrative tasks not supported by them. By digitizing and streamlining processes like referrals, patient intake, and care coordination—often still managed through faxes, emails, and spreadsheets—Dock Health aims to reduce redundancy, improve visibility, and enhance the overall user experience for healthcare organizations of all sizes.</p>
<p>The conversation also focuses on the role of AI and automation in transforming healthcare operations. Dr. Docktor highlights Dock Health’s “AI‑first” approach, incorporating generative AI and agentic models to automate routine tasks while keeping humans in the loop for oversight. He envisions a near future where administrative inefficiencies are largely eliminated, giving clinicians more time with patients. Dr. Docktor also describes AI as the <em>“big unlock”</em> that could massively reduce the trillions wasted annually in healthcare administration, making care more efficient, accessible, and patient‑centered. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Michael Docktor, MD, Co-founder and CEO of Dock Health
In this episode, Dr. Michael Docktor, Co-founder and CEO at Dock Health, shares his journey from being a pediatric gastroenterologist at Boston Children’s Hospital to building a healthcare technology company. Inspired by his sister’s medical experiences and his family’s design background, Dr. Doctor combined medicine, design, and technology to address inefficiencies in operational workflows, particularly the administrative burdens that weigh heavily on providers and staff.
Dr. Docktor explains how Dock Health was created to serve as a productivity platform for healthcare, filling the gap between electronic health records (EHRs) and the countless administrative tasks not supported by them. By digitizing and streamlining processes like referrals, patient intake, and care coordination—often still managed through faxes, emails, and spreadsheets—Dock Health aims to reduce redundancy, improve visibility, and enhance the overall user experience for healthcare organizations of all sizes.
The conversation also focuses on the role of AI and automation in transforming healthcare operations. Dr. Docktor highlights Dock Health’s “AI‑first” approach, incorporating generative AI and agentic models to automate routine tasks while keeping humans in the loop for oversight. He envisions a near future where administrative inefficiencies are largely eliminated, giving clinicians more time with patients. Dr. Docktor also describes AI as the “big unlock” that could massively reduce the trillions wasted annually in healthcare administration, making care more efficient, accessible, and patient‑centered. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI, Design, and the Future of Operational Workflows in Unlocking Healthcare Efficiency]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/michael-docktor-md-co-founder-and-ceo-of-dock-health" title="Michael Docktor, MD, Co-founder and CEO of Dock Health" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Michael Docktor, MD, Co-founder and CEO of Dock Health</a>
<p>In this episode, Dr. Michael Docktor, Co-founder and CEO at Dock Health, shares his journey from being a pediatric gastroenterologist at Boston Children’s Hospital to building a healthcare technology company. Inspired by his sister’s medical experiences and his family’s design background, Dr. Doctor combined medicine, design, and technology to address inefficiencies in operational workflows, particularly the administrative burdens that weigh heavily on providers and staff.</p>
<p>Dr. Docktor explains how Dock Health was created to serve as a productivity platform for healthcare, filling the gap between electronic health records (EHRs) and the countless administrative tasks not supported by them. By digitizing and streamlining processes like referrals, patient intake, and care coordination—often still managed through faxes, emails, and spreadsheets—Dock Health aims to reduce redundancy, improve visibility, and enhance the overall user experience for healthcare organizations of all sizes.</p>
<p>The conversation also focuses on the role of AI and automation in transforming healthcare operations. Dr. Docktor highlights Dock Health’s “AI‑first” approach, incorporating generative AI and agentic models to automate routine tasks while keeping humans in the loop for oversight. He envisions a near future where administrative inefficiencies are largely eliminated, giving clinicians more time with patients. Dr. Docktor also describes AI as the <em>“big unlock”</em> that could massively reduce the trillions wasted annually in healthcare administration, making care more efficient, accessible, and patient‑centered. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2135488/c1e-33kkikdqd7fkqr9z-8dq11nkvsq3w-uqfcan.mp3" length="26244729"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Michael Docktor, MD, Co-founder and CEO of Dock Health
In this episode, Dr. Michael Docktor, Co-founder and CEO at Dock Health, shares his journey from being a pediatric gastroenterologist at Boston Children’s Hospital to building a healthcare technology company. Inspired by his sister’s medical experiences and his family’s design background, Dr. Doctor combined medicine, design, and technology to address inefficiencies in operational workflows, particularly the administrative burdens that weigh heavily on providers and staff.
Dr. Docktor explains how Dock Health was created to serve as a productivity platform for healthcare, filling the gap between electronic health records (EHRs) and the countless administrative tasks not supported by them. By digitizing and streamlining processes like referrals, patient intake, and care coordination—often still managed through faxes, emails, and spreadsheets—Dock Health aims to reduce redundancy, improve visibility, and enhance the overall user experience for healthcare organizations of all sizes.
The conversation also focuses on the role of AI and automation in transforming healthcare operations. Dr. Docktor highlights Dock Health’s “AI‑first” approach, incorporating generative AI and agentic models to automate routine tasks while keeping humans in the loop for oversight. He envisions a near future where administrative inefficiencies are largely eliminated, giving clinicians more time with patients. Dr. Docktor also describes AI as the “big unlock” that could massively reduce the trillions wasted annually in healthcare administration, making care more efficient, accessible, and patient‑centered. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2135488/c1a-gd22-gpzgg6gpto5n-qanuei.png"></itunes:image>
                                                                            <itunes:duration>00:27:21</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Using AI to Ease Clinician Burden and Deliver Real Value in Healthcare]]>
                </title>
                <pubDate>Mon, 25 Aug 2025 04:13:53 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2121040</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/using-ai-to-ease-clinician-burden-and-deliver-real-value-in-healthcare</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/sameer-sethi-svp-chief-ai-insights-officer-hackensack-meridian-health" title="Sameer Sethi, SVP, Chief AI &amp; Insights Officer, Hackensack Meridian Health" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Sameer Sethi, SVP, Chief AI &amp; Insights Officer, Hackensack Meridian Health</a>
<p>In this episode, Sameer Sethi, SVP and Chief AI &amp; Insights Officer at Hackensack Meridian Health, shares how the health system is embedding AI directly into clinician workflows, moving from theory to real-world transformation.</p>
<p>Sameer outlines practical applications such as specialty-specific clinical note summarization, which reduces “pajama time” for physicians and improves patient interactions, and sentiment analysis of patient survey data, which surfaces actionable insights at scale. He also describes Hackensack’s AI governance framework – a board-approved structure with six strategic focus areas, guided by cross-departmental representation to ensure safe, effective adoption.</p>
<p>Emphasizing that AI solutions serve as decision-support rather than decision-making tools, Sameer highlights the importance of keeping a “human in the loop.” He sees agentic AI as the next frontier – integrating LLMs, RPA, and rule engines to automate complex processes such as prior authorizations and denial management. The result: faster workflows, administrative efficiency, and truly personalized care at scale. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Sameer Sethi, SVP, Chief AI & Insights Officer, Hackensack Meridian Health
In this episode, Sameer Sethi, SVP and Chief AI & Insights Officer at Hackensack Meridian Health, shares how the health system is embedding AI directly into clinician workflows, moving from theory to real-world transformation.
Sameer outlines practical applications such as specialty-specific clinical note summarization, which reduces “pajama time” for physicians and improves patient interactions, and sentiment analysis of patient survey data, which surfaces actionable insights at scale. He also describes Hackensack’s AI governance framework – a board-approved structure with six strategic focus areas, guided by cross-departmental representation to ensure safe, effective adoption.
Emphasizing that AI solutions serve as decision-support rather than decision-making tools, Sameer highlights the importance of keeping a “human in the loop.” He sees agentic AI as the next frontier – integrating LLMs, RPA, and rule engines to automate complex processes such as prior authorizations and denial management. The result: faster workflows, administrative efficiency, and truly personalized care at scale. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Using AI to Ease Clinician Burden and Deliver Real Value in Healthcare]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock</a> · <a href="https://soundcloud.com/thebigunlock/sameer-sethi-svp-chief-ai-insights-officer-hackensack-meridian-health" title="Sameer Sethi, SVP, Chief AI &amp; Insights Officer, Hackensack Meridian Health" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Sameer Sethi, SVP, Chief AI &amp; Insights Officer, Hackensack Meridian Health</a>
<p>In this episode, Sameer Sethi, SVP and Chief AI &amp; Insights Officer at Hackensack Meridian Health, shares how the health system is embedding AI directly into clinician workflows, moving from theory to real-world transformation.</p>
<p>Sameer outlines practical applications such as specialty-specific clinical note summarization, which reduces “pajama time” for physicians and improves patient interactions, and sentiment analysis of patient survey data, which surfaces actionable insights at scale. He also describes Hackensack’s AI governance framework – a board-approved structure with six strategic focus areas, guided by cross-departmental representation to ensure safe, effective adoption.</p>
<p>Emphasizing that AI solutions serve as decision-support rather than decision-making tools, Sameer highlights the importance of keeping a “human in the loop.” He sees agentic AI as the next frontier – integrating LLMs, RPA, and rule engines to automate complex processes such as prior authorizations and denial management. The result: faster workflows, administrative efficiency, and truly personalized care at scale. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2121040/c1e-wnzzb3ko7gu0g6q2-9jqm52wdfwg4-a9xneg.mp3" length="31879650"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Sameer Sethi, SVP, Chief AI & Insights Officer, Hackensack Meridian Health
In this episode, Sameer Sethi, SVP and Chief AI & Insights Officer at Hackensack Meridian Health, shares how the health system is embedding AI directly into clinician workflows, moving from theory to real-world transformation.
Sameer outlines practical applications such as specialty-specific clinical note summarization, which reduces “pajama time” for physicians and improves patient interactions, and sentiment analysis of patient survey data, which surfaces actionable insights at scale. He also describes Hackensack’s AI governance framework – a board-approved structure with six strategic focus areas, guided by cross-departmental representation to ensure safe, effective adoption.
Emphasizing that AI solutions serve as decision-support rather than decision-making tools, Sameer highlights the importance of keeping a “human in the loop.” He sees agentic AI as the next frontier – integrating LLMs, RPA, and rule engines to automate complex processes such as prior authorizations and denial management. The result: faster workflows, administrative efficiency, and truly personalized care at scale. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2121040/c1a-gd22-xx40vmj3appk-tkzm2p.png"></itunes:image>
                                                                            <itunes:duration>00:33:13</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Price Transparency, Data, and AI for a Better Healthcare Experience]]>
                </title>
                <pubDate>Thu, 21 Aug 2025 08:30:40 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2116191</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/price-transparency-data-and-ai-for-a-better-healthcare-experience</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Ramesh Kumar, CEO and Co-Founder, zakipoint Health" href="https://soundcloud.com/thebigunlock/ramesh-kumar-ceo-and-co-founder-zakipoint-health" target="_blank" rel="noreferrer noopener">Ramesh Kumar, CEO and Co-Founder, zakipoint Health</a>
<p>In this episode, Ramesh Kumar, CEO and Co-founder of Zakipoint Health, shares his perspective on addressing healthcare’s persistent challenges—high costs, lack of price transparency, and fragmented care. He emphasizes that patients, or ‘members,’ often struggle to understand the true value of care, even as regulatory pushes for transparency continue.</p>
<p>Ramesh highlights how greater data visibility and patient empowerment can shift the system toward value-based outcomes. He emphasizes that true digital transformation goes beyond compliance and organizations must leverage transparency in data to create actionable insights for patients, employers, and providers alike. He also discusses the role of AI and agentic AI in simplifying complexity, reducing administrative burden, and enabling more personalized, efficient care delivery.</p>
<p>Ramesh underscores the need for co-creation between payers, providers, and technology innovators to build sustainable solutions. For him, the convergence of transparency, digital innovation, and AI marks a pivotal moment to reimagine healthcare’s future. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Ramesh Kumar, CEO and Co-Founder, zakipoint Health
In this episode, Ramesh Kumar, CEO and Co-founder of Zakipoint Health, shares his perspective on addressing healthcare’s persistent challenges—high costs, lack of price transparency, and fragmented care. He emphasizes that patients, or ‘members,’ often struggle to understand the true value of care, even as regulatory pushes for transparency continue.
Ramesh highlights how greater data visibility and patient empowerment can shift the system toward value-based outcomes. He emphasizes that true digital transformation goes beyond compliance and organizations must leverage transparency in data to create actionable insights for patients, employers, and providers alike. He also discusses the role of AI and agentic AI in simplifying complexity, reducing administrative burden, and enabling more personalized, efficient care delivery.
Ramesh underscores the need for co-creation between payers, providers, and technology innovators to build sustainable solutions. For him, the convergence of transparency, digital innovation, and AI marks a pivotal moment to reimagine healthcare’s future. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Price Transparency, Data, and AI for a Better Healthcare Experience]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Ramesh Kumar, CEO and Co-Founder, zakipoint Health" href="https://soundcloud.com/thebigunlock/ramesh-kumar-ceo-and-co-founder-zakipoint-health" target="_blank" rel="noreferrer noopener">Ramesh Kumar, CEO and Co-Founder, zakipoint Health</a>
<p>In this episode, Ramesh Kumar, CEO and Co-founder of Zakipoint Health, shares his perspective on addressing healthcare’s persistent challenges—high costs, lack of price transparency, and fragmented care. He emphasizes that patients, or ‘members,’ often struggle to understand the true value of care, even as regulatory pushes for transparency continue.</p>
<p>Ramesh highlights how greater data visibility and patient empowerment can shift the system toward value-based outcomes. He emphasizes that true digital transformation goes beyond compliance and organizations must leverage transparency in data to create actionable insights for patients, employers, and providers alike. He also discusses the role of AI and agentic AI in simplifying complexity, reducing administrative burden, and enabling more personalized, efficient care delivery.</p>
<p>Ramesh underscores the need for co-creation between payers, providers, and technology innovators to build sustainable solutions. For him, the convergence of transparency, digital innovation, and AI marks a pivotal moment to reimagine healthcare’s future. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2116191/c1e-60ddion5r6indw39-gpz021kkbpkx-fhfnw4.mp3" length="20098983"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Ramesh Kumar, CEO and Co-Founder, zakipoint Health
In this episode, Ramesh Kumar, CEO and Co-founder of Zakipoint Health, shares his perspective on addressing healthcare’s persistent challenges—high costs, lack of price transparency, and fragmented care. He emphasizes that patients, or ‘members,’ often struggle to understand the true value of care, even as regulatory pushes for transparency continue.
Ramesh highlights how greater data visibility and patient empowerment can shift the system toward value-based outcomes. He emphasizes that true digital transformation goes beyond compliance and organizations must leverage transparency in data to create actionable insights for patients, employers, and providers alike. He also discusses the role of AI and agentic AI in simplifying complexity, reducing administrative burden, and enabling more personalized, efficient care delivery.
Ramesh underscores the need for co-creation between payers, providers, and technology innovators to build sustainable solutions. For him, the convergence of transparency, digital innovation, and AI marks a pivotal moment to reimagine healthcare’s future. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2116191/c1a-gd22-jp3g4o35u7r4-2eajqn.png"></itunes:image>
                                                                            <itunes:duration>00:20:57</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI and the Future of Longevity-Driven Personalized Care]]>
                </title>
                <pubDate>Mon, 18 Aug 2025 11:48:38 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2113894</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-and-the-future-of-longevity-driven-personalized-care</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Regina Druz, Founder and CEO, Holistic Heart Centers" href="https://soundcloud.com/thebigunlock/dr-regina-druz-founder-and-ceo-holistic-heart-centers" target="_blank" rel="noreferrer noopener">Dr. Regina Druz, Founder and CEO, Holistic Heart Centers</a>
<p>In this episode, Dr. Regina Druz, Founder and CEO at Holistic Heart Centers, shares her journey from conventional hospital-based cardiology to leading the charge in personalized precision medicine and longevity-focused care. She explains why optimizing health is the cornerstone of extending lifespan and how digital health innovations must deliver value for patients, clinicians, and caregivers—improving outcomes, reducing burnout, lowering costs, and meeting regulatory demands.</p>
<p>A pioneer in telemedicine, digital devices, and AI tools such as ambient scribes and large language models, Dr. Druz examines the opportunities and challenges of Agentic AI in transforming healthcare workflows. She envisions a near future where AI goes beyond administrative tasks to provide advanced clinical decision support—predicting and preventing conditions like Alzheimer’s and heart failure years before symptoms arise.</p>
<p>For Dr. Druz, the “N-of-1” approach—tailoring care to each individual’s unique biology and circumstances—will become the new standard, redefining population health through truly personalized care. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Dr. Regina Druz, Founder and CEO, Holistic Heart Centers
In this episode, Dr. Regina Druz, Founder and CEO at Holistic Heart Centers, shares her journey from conventional hospital-based cardiology to leading the charge in personalized precision medicine and longevity-focused care. She explains why optimizing health is the cornerstone of extending lifespan and how digital health innovations must deliver value for patients, clinicians, and caregivers—improving outcomes, reducing burnout, lowering costs, and meeting regulatory demands.
A pioneer in telemedicine, digital devices, and AI tools such as ambient scribes and large language models, Dr. Druz examines the opportunities and challenges of Agentic AI in transforming healthcare workflows. She envisions a near future where AI goes beyond administrative tasks to provide advanced clinical decision support—predicting and preventing conditions like Alzheimer’s and heart failure years before symptoms arise.
For Dr. Druz, the “N-of-1” approach—tailoring care to each individual’s unique biology and circumstances—will become the new standard, redefining population health through truly personalized care. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI and the Future of Longevity-Driven Personalized Care]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Dr. Regina Druz, Founder and CEO, Holistic Heart Centers" href="https://soundcloud.com/thebigunlock/dr-regina-druz-founder-and-ceo-holistic-heart-centers" target="_blank" rel="noreferrer noopener">Dr. Regina Druz, Founder and CEO, Holistic Heart Centers</a>
<p>In this episode, Dr. Regina Druz, Founder and CEO at Holistic Heart Centers, shares her journey from conventional hospital-based cardiology to leading the charge in personalized precision medicine and longevity-focused care. She explains why optimizing health is the cornerstone of extending lifespan and how digital health innovations must deliver value for patients, clinicians, and caregivers—improving outcomes, reducing burnout, lowering costs, and meeting regulatory demands.</p>
<p>A pioneer in telemedicine, digital devices, and AI tools such as ambient scribes and large language models, Dr. Druz examines the opportunities and challenges of Agentic AI in transforming healthcare workflows. She envisions a near future where AI goes beyond administrative tasks to provide advanced clinical decision support—predicting and preventing conditions like Alzheimer’s and heart failure years before symptoms arise.</p>
<p>For Dr. Druz, the “N-of-1” approach—tailoring care to each individual’s unique biology and circumstances—will become the new standard, redefining population health through truly personalized care. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2113894/c1e-49ggu1kvqqbop756-5zo439dgf0kp-mre00m.mp3" length="31432626"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Dr. Regina Druz, Founder and CEO, Holistic Heart Centers
In this episode, Dr. Regina Druz, Founder and CEO at Holistic Heart Centers, shares her journey from conventional hospital-based cardiology to leading the charge in personalized precision medicine and longevity-focused care. She explains why optimizing health is the cornerstone of extending lifespan and how digital health innovations must deliver value for patients, clinicians, and caregivers—improving outcomes, reducing burnout, lowering costs, and meeting regulatory demands.
A pioneer in telemedicine, digital devices, and AI tools such as ambient scribes and large language models, Dr. Druz examines the opportunities and challenges of Agentic AI in transforming healthcare workflows. She envisions a near future where AI goes beyond administrative tasks to provide advanced clinical decision support—predicting and preventing conditions like Alzheimer’s and heart failure years before symptoms arise.
For Dr. Druz, the “N-of-1” approach—tailoring care to each individual’s unique biology and circumstances—will become the new standard, redefining population health through truly personalized care. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2113894/c1a-gd22-gpz157rgfow-znnxlf.png"></itunes:image>
                                                                            <itunes:duration>00:32:45</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation]]>
                </title>
                <pubDate>Mon, 11 Aug 2025 08:28:39 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2108276</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/digital-twins-could-be-a-game-changer-for-scalable-healthcare-innovation</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation - Podcast with Inderpal Kohli" href="https://soundcloud.com/thebigunlock/digital-twins-could-be-a-game-changer-for-scalable-healthcare-innovation-podcast-with-inderpal-kohli" target="_blank" rel="noreferrer noopener">Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation – Podcast with Inderpal Kohli</a>
<p>In this episode, Inderpal Kohli, Healthcare Executive Leader (Englewood Health, HSS, and Columbia University Medical Center), shares his vision for scalable digital health transformation. He outlines a proven framework focused on patient engagement, clinically integrated care, and remote patient monitoring—strategies that have already driven an 18–20% increase in online scheduling and improved outcomes in preventive care campaigns.</p>
<p>Inderpal also reflects on how a chance project in biomedical informatics sparked his passion for digital transformation, leading to pioneering work in digital pathology, remote monitoring, and digital front door solutions. He explores the promise of ambient documentation in reducing clinician burden and enhancing satisfaction, and addresses the persistent challenge of integrating EHR systems with third-party tools—stressing the importance of seamless integration for meaningful impact.</p>
<p>He also discusses the potential of digital twins as a game-changer, shares lessons on building agile, consumer-focused digital teams, and weighs in on how GenAI and agentic automation are poised to reshape care delivery. Take a listen. </p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock · Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation – Podcast with Inderpal Kohli
In this episode, Inderpal Kohli, Healthcare Executive Leader (Englewood Health, HSS, and Columbia University Medical Center), shares his vision for scalable digital health transformation. He outlines a proven framework focused on patient engagement, clinically integrated care, and remote patient monitoring—strategies that have already driven an 18–20% increase in online scheduling and improved outcomes in preventive care campaigns.
Inderpal also reflects on how a chance project in biomedical informatics sparked his passion for digital transformation, leading to pioneering work in digital pathology, remote monitoring, and digital front door solutions. He explores the promise of ambient documentation in reducing clinician burden and enhancing satisfaction, and addresses the persistent challenge of integrating EHR systems with third-party tools—stressing the importance of seamless integration for meaningful impact.
He also discusses the potential of digital twins as a game-changer, shares lessons on building agile, consumer-focused digital teams, and weighs in on how GenAI and agentic automation are poised to reshape care delivery. Take a listen. ]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock</a> · <a style="color:#cccccc;text-decoration:none;" title="Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation - Podcast with Inderpal Kohli" href="https://soundcloud.com/thebigunlock/digital-twins-could-be-a-game-changer-for-scalable-healthcare-innovation-podcast-with-inderpal-kohli" target="_blank" rel="noreferrer noopener">Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation – Podcast with Inderpal Kohli</a>
<p>In this episode, Inderpal Kohli, Healthcare Executive Leader (Englewood Health, HSS, and Columbia University Medical Center), shares his vision for scalable digital health transformation. He outlines a proven framework focused on patient engagement, clinically integrated care, and remote patient monitoring—strategies that have already driven an 18–20% increase in online scheduling and improved outcomes in preventive care campaigns.</p>
<p>Inderpal also reflects on how a chance project in biomedical informatics sparked his passion for digital transformation, leading to pioneering work in digital pathology, remote monitoring, and digital front door solutions. He explores the promise of ambient documentation in reducing clinician burden and enhancing satisfaction, and addresses the persistent challenge of integrating EHR systems with third-party tools—stressing the importance of seamless integration for meaningful impact.</p>
<p>He also discusses the potential of digital twins as a game-changer, shares lessons on building agile, consumer-focused digital teams, and weighs in on how GenAI and agentic automation are poised to reshape care delivery. Take a listen. </p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2108276/c1e-mq00aqd8z9swqd0p-34744284s2p6-hrqz8d.mp3" length="25653840"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock · Digital Twins Could Be a Game-Changer for Scalable Healthcare Innovation – Podcast with Inderpal Kohli
In this episode, Inderpal Kohli, Healthcare Executive Leader (Englewood Health, HSS, and Columbia University Medical Center), shares his vision for scalable digital health transformation. He outlines a proven framework focused on patient engagement, clinically integrated care, and remote patient monitoring—strategies that have already driven an 18–20% increase in online scheduling and improved outcomes in preventive care campaigns.
Inderpal also reflects on how a chance project in biomedical informatics sparked his passion for digital transformation, leading to pioneering work in digital pathology, remote monitoring, and digital front door solutions. He explores the promise of ambient documentation in reducing clinician burden and enhancing satisfaction, and addresses the persistent challenge of integrating EHR systems with third-party tools—stressing the importance of seamless integration for meaningful impact.
He also discusses the potential of digital twins as a game-changer, shares lessons on building agile, consumer-focused digital teams, and weighs in on how GenAI and agentic automation are poised to reshape care delivery. Take a listen. ]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2108276/c1a-gd22-9jqjjk4zhqwx-am4uur.png"></itunes:image>
                                                                            <itunes:duration>00:26:44</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[AI If Done Right Can Rehumanize Healthcare]]>
                </title>
                <pubDate>Mon, 04 Aug 2025 08:38:31 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2103805</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/ai-if-done-right-can-rehumanize-healthcare</link>
                                <description>
                                            <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock Podcast" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a style="color:#cccccc;text-decoration:none;" title="AI If Done Right Can Rehumanize Healthcare - Podcast with Ashis Barad" href="https://soundcloud.com/thebigunlock/ai-if-done-right-can-rehumanize-healthcare-podcast-with-ashis-barad" target="_blank" rel="noreferrer noopener">AI If Done Right Can Rehumanize Healthcare – Podcast with Ashis Barad</a>
<p>In this episode, Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS), discusses his journey in rehumanizing healthcare through digital health transformation. A practicing pediatric gastroenterologist, Ashis advocates for tech that genuinely solves problems, viewing himself as a “doctor first, technologist second.”</p>
<p>Ashis stresses on Agentic AI and change management as pivotal elements in healthcare transformation. Healthcare is inherently workflow-centric, not a series of isolated moments. Barad explains Agentic AI as a workflow orchestrator designed to reduce administrative waste, enhance patient experience, and accelerate the adoption of best practices.</p>
<p>Ashis outlines HSS’s strategy to leverage its specialized focus to build a modern data lakehouse architecture and deploy AI-powered solutions through key partnerships. He envisions rehumanizing healthcare by automating backend processes, expanding clinician-patient time, and codifying best practices that can be scaled globally, especially in musculoskeletal care and movement. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[﻿
The Big Unlock Podcast · AI If Done Right Can Rehumanize Healthcare – Podcast with Ashis Barad
In this episode, Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS), discusses his journey in rehumanizing healthcare through digital health transformation. A practicing pediatric gastroenterologist, Ashis advocates for tech that genuinely solves problems, viewing himself as a “doctor first, technologist second.”
Ashis stresses on Agentic AI and change management as pivotal elements in healthcare transformation. Healthcare is inherently workflow-centric, not a series of isolated moments. Barad explains Agentic AI as a workflow orchestrator designed to reduce administrative waste, enhance patient experience, and accelerate the adoption of best practices.
Ashis outlines HSS’s strategy to leverage its specialized focus to build a modern data lakehouse architecture and deploy AI-powered solutions through key partnerships. He envisions rehumanizing healthcare by automating backend processes, expanding clinician-patient time, and codifying best practices that can be scaled globally, especially in musculoskeletal care and movement. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[AI If Done Right Can Rehumanize Healthcare]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<p>﻿</p>
<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock Podcast" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a style="color:#cccccc;text-decoration:none;" title="AI If Done Right Can Rehumanize Healthcare - Podcast with Ashis Barad" href="https://soundcloud.com/thebigunlock/ai-if-done-right-can-rehumanize-healthcare-podcast-with-ashis-barad" target="_blank" rel="noreferrer noopener">AI If Done Right Can Rehumanize Healthcare – Podcast with Ashis Barad</a>
<p>In this episode, Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS), discusses his journey in rehumanizing healthcare through digital health transformation. A practicing pediatric gastroenterologist, Ashis advocates for tech that genuinely solves problems, viewing himself as a “doctor first, technologist second.”</p>
<p>Ashis stresses on Agentic AI and change management as pivotal elements in healthcare transformation. Healthcare is inherently workflow-centric, not a series of isolated moments. Barad explains Agentic AI as a workflow orchestrator designed to reduce administrative waste, enhance patient experience, and accelerate the adoption of best practices.</p>
<p>Ashis outlines HSS’s strategy to leverage its specialized focus to build a modern data lakehouse architecture and deploy AI-powered solutions through key partnerships. He envisions rehumanizing healthcare by automating backend processes, expanding clinician-patient time, and codifying best practices that can be scaled globally, especially in musculoskeletal care and movement. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2103805/c1e-1x00u50wdqtxvw0q-47x4wmzmu82k-f7ocov.mp3" length="35231913"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[﻿
The Big Unlock Podcast · AI If Done Right Can Rehumanize Healthcare – Podcast with Ashis Barad
In this episode, Ashis Barad, Chief Digital Technology Officer at the Hospital for Special Surgery (HSS), discusses his journey in rehumanizing healthcare through digital health transformation. A practicing pediatric gastroenterologist, Ashis advocates for tech that genuinely solves problems, viewing himself as a “doctor first, technologist second.”
Ashis stresses on Agentic AI and change management as pivotal elements in healthcare transformation. Healthcare is inherently workflow-centric, not a series of isolated moments. Barad explains Agentic AI as a workflow orchestrator designed to reduce administrative waste, enhance patient experience, and accelerate the adoption of best practices.
Ashis outlines HSS’s strategy to leverage its specialized focus to build a modern data lakehouse architecture and deploy AI-powered solutions through key partnerships. He envisions rehumanizing healthcare by automating backend processes, expanding clinician-patient time, and codifying best practices that can be scaled globally, especially in musculoskeletal care and movement. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2103805/c1a-gd22-xx4k9z80t8vq-uumxme.png"></itunes:image>
                                                                            <itunes:duration>00:36:42</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Interoperability and AI Adoption are the Pillars of Healthcare]]>
                </title>
                <pubDate>Mon, 28 Jul 2025 06:42:29 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2098664</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/interoperability-and-ai-adoption-are-the-pillars-of8s1</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock Podcast" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a href="https://soundcloud.com/thebigunlock/interoperability-and-ai-adoption-are-the-pillars-of-healthcare-podcast-with-michael-marchant" title="Interoperability and AI Adoption are the Pillars of Healthcare - Podcast with Michael Marchant" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Interoperability and AI Adoption are the Pillars of Healthcare – Podcast with Michael Marchant</a>
<p>In this episode, Michael Marchant, Director of Digital Applications at Sutter Health, shares his expert perspective on how interoperability and AI are reshaping the future of healthcare. He discusses the promise of TEFCA (Trusted Exchange Framework and Common Agreement) in expanding data exchange beyond treatment to support broader care coordination. He also highlights California’s Data Exchange Framework as a model for equitable and inclusive health information sharing across diverse communities.</p>
<p>The conversation explores the real-world applications of generative AI in clinical settings, from ambient documentation to AI-powered inbox agents that reduce administrative burden and help clinicians deliver faster, more personalized care.</p>
<p>Michael emphasizes the importance of assistive, not autonomous, AI, spotlighting use cases where technology enhances the capabilities of care teams without replacing the human touch. Drawing on decades of experience in health IT and data policy, Michael offers a grounded yet visionary take on building scalable, interoperable, and patient-centered digital ecosystems. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock Podcast · Interoperability and AI Adoption are the Pillars of Healthcare – Podcast with Michael Marchant
In this episode, Michael Marchant, Director of Digital Applications at Sutter Health, shares his expert perspective on how interoperability and AI are reshaping the future of healthcare. He discusses the promise of TEFCA (Trusted Exchange Framework and Common Agreement) in expanding data exchange beyond treatment to support broader care coordination. He also highlights California’s Data Exchange Framework as a model for equitable and inclusive health information sharing across diverse communities.
The conversation explores the real-world applications of generative AI in clinical settings, from ambient documentation to AI-powered inbox agents that reduce administrative burden and help clinicians deliver faster, more personalized care.
Michael emphasizes the importance of assistive, not autonomous, AI, spotlighting use cases where technology enhances the capabilities of care teams without replacing the human touch. Drawing on decades of experience in health IT and data policy, Michael offers a grounded yet visionary take on building scalable, interoperable, and patient-centered digital ecosystems. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Interoperability and AI Adoption are the Pillars of Healthcare]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock Podcast" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a href="https://soundcloud.com/thebigunlock/interoperability-and-ai-adoption-are-the-pillars-of-healthcare-podcast-with-michael-marchant" title="Interoperability and AI Adoption are the Pillars of Healthcare - Podcast with Michael Marchant" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Interoperability and AI Adoption are the Pillars of Healthcare – Podcast with Michael Marchant</a>
<p>In this episode, Michael Marchant, Director of Digital Applications at Sutter Health, shares his expert perspective on how interoperability and AI are reshaping the future of healthcare. He discusses the promise of TEFCA (Trusted Exchange Framework and Common Agreement) in expanding data exchange beyond treatment to support broader care coordination. He also highlights California’s Data Exchange Framework as a model for equitable and inclusive health information sharing across diverse communities.</p>
<p>The conversation explores the real-world applications of generative AI in clinical settings, from ambient documentation to AI-powered inbox agents that reduce administrative burden and help clinicians deliver faster, more personalized care.</p>
<p>Michael emphasizes the importance of assistive, not autonomous, AI, spotlighting use cases where technology enhances the capabilities of care teams without replacing the human touch. Drawing on decades of experience in health IT and data policy, Michael offers a grounded yet visionary take on building scalable, interoperable, and patient-centered digital ecosystems. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2098664/c1e-jk44a54xk8bn1zd6-6z3qgkmpsng3-ksbfde.mp3" length="30618642"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock Podcast · Interoperability and AI Adoption are the Pillars of Healthcare – Podcast with Michael Marchant
In this episode, Michael Marchant, Director of Digital Applications at Sutter Health, shares his expert perspective on how interoperability and AI are reshaping the future of healthcare. He discusses the promise of TEFCA (Trusted Exchange Framework and Common Agreement) in expanding data exchange beyond treatment to support broader care coordination. He also highlights California’s Data Exchange Framework as a model for equitable and inclusive health information sharing across diverse communities.
The conversation explores the real-world applications of generative AI in clinical settings, from ambient documentation to AI-powered inbox agents that reduce administrative burden and help clinicians deliver faster, more personalized care.
Michael emphasizes the importance of assistive, not autonomous, AI, spotlighting use cases where technology enhances the capabilities of care teams without replacing the human touch. Drawing on decades of experience in health IT and data policy, Michael offers a grounded yet visionary take on building scalable, interoperable, and patient-centered digital ecosystems. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2098664/c1a-gd22-ndzv85r7ux2-jdj76l.png"></itunes:image>
                                                                            <itunes:duration>00:31:54</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Transforming Wellness-First Senior Communities Through AI and Social Determinants]]>
                </title>
                <pubDate>Mon, 21 Jul 2025 07:30:08 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2093929</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/transforming-wellness-first-senior-communities-throuozw</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock Podcast" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a href="https://soundcloud.com/thebigunlock/transforming-wellness-first-senior-communities-through-ai-and-social-determinants-podcast-with-mike-hughes" title="Transforming Wellness-First Senior Communities Through AI and Social Determinants - Podcast with Mike Hughes" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Transforming Wellness-First Senior Communities Through AI and Social Determinants – Podcast with Mike Hughes</a>
<p>In this episode, Michael Hughes, Senior EVP, Chief Transformation and Innovation Officer at United Church Homes, shares how the organization is reshaping the future of senior living. Moving beyond a traditional housing-first model, United Church Homes is leading a shift toward a wellness-first approach that prioritizes health, dignity, and independence for older adults. </p>
<p>With more than 100 communities across 15 states, the organization is leveraging scalable, data-driven strategies to support aging in place, particularly for vulnerable populations. Mike explains how understanding and addressing social determinants of health (SDOH) is key to improving outcomes, and how machine learning is helping evaluate the impact of non-clinical interventions in real-world settings.</p>
<p>From transitioning fall detection to fall prevention, to exploring lightweight sensor technologies, Mike emphasizes the importance of proactive care and personal motivation in sustaining long-term wellness. He also introduces the organization’s Entrepreneur-in-Residence (EIR) program—a unique initiative that brings innovators into senior communities to co-create human-centered solutions rooted in real-life experience. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock Podcast · Transforming Wellness-First Senior Communities Through AI and Social Determinants – Podcast with Mike Hughes
In this episode, Michael Hughes, Senior EVP, Chief Transformation and Innovation Officer at United Church Homes, shares how the organization is reshaping the future of senior living. Moving beyond a traditional housing-first model, United Church Homes is leading a shift toward a wellness-first approach that prioritizes health, dignity, and independence for older adults. 
With more than 100 communities across 15 states, the organization is leveraging scalable, data-driven strategies to support aging in place, particularly for vulnerable populations. Mike explains how understanding and addressing social determinants of health (SDOH) is key to improving outcomes, and how machine learning is helping evaluate the impact of non-clinical interventions in real-world settings.
From transitioning fall detection to fall prevention, to exploring lightweight sensor technologies, Mike emphasizes the importance of proactive care and personal motivation in sustaining long-term wellness. He also introduces the organization’s Entrepreneur-in-Residence (EIR) program—a unique initiative that brings innovators into senior communities to co-create human-centered solutions rooted in real-life experience. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Transforming Wellness-First Senior Communities Through AI and Social Determinants]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock Podcast" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a href="https://soundcloud.com/thebigunlock/transforming-wellness-first-senior-communities-through-ai-and-social-determinants-podcast-with-mike-hughes" title="Transforming Wellness-First Senior Communities Through AI and Social Determinants - Podcast with Mike Hughes" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Transforming Wellness-First Senior Communities Through AI and Social Determinants – Podcast with Mike Hughes</a>
<p>In this episode, Michael Hughes, Senior EVP, Chief Transformation and Innovation Officer at United Church Homes, shares how the organization is reshaping the future of senior living. Moving beyond a traditional housing-first model, United Church Homes is leading a shift toward a wellness-first approach that prioritizes health, dignity, and independence for older adults. </p>
<p>With more than 100 communities across 15 states, the organization is leveraging scalable, data-driven strategies to support aging in place, particularly for vulnerable populations. Mike explains how understanding and addressing social determinants of health (SDOH) is key to improving outcomes, and how machine learning is helping evaluate the impact of non-clinical interventions in real-world settings.</p>
<p>From transitioning fall detection to fall prevention, to exploring lightweight sensor technologies, Mike emphasizes the importance of proactive care and personal motivation in sustaining long-term wellness. He also introduces the organization’s Entrepreneur-in-Residence (EIR) program—a unique initiative that brings innovators into senior communities to co-create human-centered solutions rooted in real-life experience. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2093929/c1e-mq00aq4j4ktwqd0p-z3k27wr2u3xr-lbqfdy.mp3" length="22796556"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock Podcast · Transforming Wellness-First Senior Communities Through AI and Social Determinants – Podcast with Mike Hughes
In this episode, Michael Hughes, Senior EVP, Chief Transformation and Innovation Officer at United Church Homes, shares how the organization is reshaping the future of senior living. Moving beyond a traditional housing-first model, United Church Homes is leading a shift toward a wellness-first approach that prioritizes health, dignity, and independence for older adults. 
With more than 100 communities across 15 states, the organization is leveraging scalable, data-driven strategies to support aging in place, particularly for vulnerable populations. Mike explains how understanding and addressing social determinants of health (SDOH) is key to improving outcomes, and how machine learning is helping evaluate the impact of non-clinical interventions in real-world settings.
From transitioning fall detection to fall prevention, to exploring lightweight sensor technologies, Mike emphasizes the importance of proactive care and personal motivation in sustaining long-term wellness. He also introduces the organization’s Entrepreneur-in-Residence (EIR) program—a unique initiative that brings innovators into senior communities to co-create human-centered solutions rooted in real-life experience. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2093929/c1a-gd22-7z935m7wirx-nag42h.png"></itunes:image>
                                                                            <itunes:duration>00:23:45</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
                </itunes:author>
                            </item>
                    <item>
                <title>
                    <![CDATA[Building Value Through Real-World AI and Smart Technology Adoption]]>
                </title>
                <pubDate>Mon, 14 Jul 2025 08:47:43 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
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                                    <link>https://the-big-unlock.castos.com/episodes/building-value-through-real-world-ai-and-smart-techntnn</link>
                                <description>
                                            <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock Podcast" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a href="https://soundcloud.com/thebigunlock/building-value-through-real-world-ai-and-smart-technology-adoption-podcast-with-jd-whitlock" title="Building Value Through Real-World AI and Smart Technology Adoption - Podcast with J.D. Whitlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Building Value Through Real-World AI and Smart Technology Adoption – Podcast with J.D. Whitlock</a>
<p>In this episode, J.D. Whitlock, Chief Information Officer at Dayton Children’s Hospital, discusses how a smaller pediatric health system is embracing digital transformation and generative AI while navigating resource constraints.</p>
<p>Mr. Whitlock shares how platforms like Epic, Workday, and Microsoft are enabling innovation from within, especially through features like ambient documentation and coding assistance. With a fast-follower mindset, Dayton Children’s focuses on adopting proven tools from peer organizations rather than being the first to experiment. Mr. Whitlock emphasizes the importance of balancing hard ROI with softer benefits such as improving physician satisfaction and reducing burnout.</p>
<p>He also discusses the challenges of innovation in pediatric care, where many AI tools are still designed with adult medicine in mind. From building data infrastructure to enabling smarter imaging through a vendor-neutral archive, Mr. Whitlock highlights the importance of governance, strategic procurement, and cross-functional collaboration in delivering sustainable innovation. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock Podcast · Building Value Through Real-World AI and Smart Technology Adoption – Podcast with J.D. Whitlock
In this episode, J.D. Whitlock, Chief Information Officer at Dayton Children’s Hospital, discusses how a smaller pediatric health system is embracing digital transformation and generative AI while navigating resource constraints.
Mr. Whitlock shares how platforms like Epic, Workday, and Microsoft are enabling innovation from within, especially through features like ambient documentation and coding assistance. With a fast-follower mindset, Dayton Children’s focuses on adopting proven tools from peer organizations rather than being the first to experiment. Mr. Whitlock emphasizes the importance of balancing hard ROI with softer benefits such as improving physician satisfaction and reducing burnout.
He also discusses the challenges of innovation in pediatric care, where many AI tools are still designed with adult medicine in mind. From building data infrastructure to enabling smarter imaging through a vendor-neutral archive, Mr. Whitlock highlights the importance of governance, strategic procurement, and cross-functional collaboration in delivering sustainable innovation. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Building Value Through Real-World AI and Smart Technology Adoption]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a href="https://soundcloud.com/thebigunlock" title="The Big Unlock Podcast" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a href="https://soundcloud.com/thebigunlock/building-value-through-real-world-ai-and-smart-technology-adoption-podcast-with-jd-whitlock" title="Building Value Through Real-World AI and Smart Technology Adoption - Podcast with J.D. Whitlock" target="_blank" style="color:#cccccc;text-decoration:none;" rel="noreferrer noopener">Building Value Through Real-World AI and Smart Technology Adoption – Podcast with J.D. Whitlock</a>
<p>In this episode, J.D. Whitlock, Chief Information Officer at Dayton Children’s Hospital, discusses how a smaller pediatric health system is embracing digital transformation and generative AI while navigating resource constraints.</p>
<p>Mr. Whitlock shares how platforms like Epic, Workday, and Microsoft are enabling innovation from within, especially through features like ambient documentation and coding assistance. With a fast-follower mindset, Dayton Children’s focuses on adopting proven tools from peer organizations rather than being the first to experiment. Mr. Whitlock emphasizes the importance of balancing hard ROI with softer benefits such as improving physician satisfaction and reducing burnout.</p>
<p>He also discusses the challenges of innovation in pediatric care, where many AI tools are still designed with adult medicine in mind. From building data infrastructure to enabling smarter imaging through a vendor-neutral archive, Mr. Whitlock highlights the importance of governance, strategic procurement, and cross-functional collaboration in delivering sustainable innovation. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2087669/c1e-1x00u5n7djsxvw0q-347ndk6vu6qq-7ig1pf.mp3" length="24632190"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock Podcast · Building Value Through Real-World AI and Smart Technology Adoption – Podcast with J.D. Whitlock
In this episode, J.D. Whitlock, Chief Information Officer at Dayton Children’s Hospital, discusses how a smaller pediatric health system is embracing digital transformation and generative AI while navigating resource constraints.
Mr. Whitlock shares how platforms like Epic, Workday, and Microsoft are enabling innovation from within, especially through features like ambient documentation and coding assistance. With a fast-follower mindset, Dayton Children’s focuses on adopting proven tools from peer organizations rather than being the first to experiment. Mr. Whitlock emphasizes the importance of balancing hard ROI with softer benefits such as improving physician satisfaction and reducing burnout.
He also discusses the challenges of innovation in pediatric care, where many AI tools are still designed with adult medicine in mind. From building data infrastructure to enabling smarter imaging through a vendor-neutral archive, Mr. Whitlock highlights the importance of governance, strategic procurement, and cross-functional collaboration in delivering sustainable innovation. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2087669/c1a-gd22-5zo1xg50bn4-iowpfa.png"></itunes:image>
                                                                            <itunes:duration>00:25:40</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
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                    <item>
                <title>
                    <![CDATA[Aligning AI Fundamentals with User Experience in Pharma]]>
                </title>
                <pubDate>Mon, 07 Jul 2025 07:47:31 +0000</pubDate>
                <dc:creator>Rohit Mahajan &amp; Ritu M. Uberoy</dc:creator>
                <guid isPermaLink="true">
                    https://permalink.castos.com/podcast/5282/episode/2082222</guid>
                                    <link>https://the-big-unlock.castos.com/episodes/aligning-ai-fundamentals-with-user-experience-in-phatxe</link>
                                <description>
                                            <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock Podcast" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a style="color:#cccccc;text-decoration:none;" title="Aligning AI Fundamentals with User Experience in Pharma - Podcast with Alicia Abella" href="https://soundcloud.com/thebigunlock/aligning-ai-fundamentals-with-user-experience-in-pharma-podcast-with-alicia-abella" target="_blank" rel="noreferrer noopener">Aligning AI Fundamentals with User Experience in Pharma – Podcast with Alicia Abella</a>
<p>In this episode, Alicia Abella, AI Product Lead at Novo Nordisk, discusses how she is helping drive responsible AI adoption in the pharmaceutical industry. She shares her early experiences in AI, starting with her PhD research at Columbia University on image processing and natural language processing. </p>
<p>At Novo Nordisk, the current focus is on applying AI to commercialization functions including – marketing, legal, and HR – beyond its traditional use in drug discovery. Alicia highlights key use cases such as generative AI for knowledge search, content generation for marketing campaigns, and traditional AI techniques for deriving insights about healthcare providers. She also emphasizes the importance of applying a product mindset to AI development by evaluating user needs, business value, and compliance from the outset.</p>
<p>Alicia notes that adding effective governance can help innovation move in the right direction. She also talks about an internal AI Ambassador Program and emphasizes the importance of designing intuitive AI tools to increase adoption. She concludes by discussing future trends in AI, including contextual intelligence, user-centric design, and the opportunity for AI to enhance, rather than replace human decision-making. Take a listen.</p>]]>
                                    </description>
                <itunes:subtitle>
                    <![CDATA[The Big Unlock Podcast · Aligning AI Fundamentals with User Experience in Pharma – Podcast with Alicia Abella
In this episode, Alicia Abella, AI Product Lead at Novo Nordisk, discusses how she is helping drive responsible AI adoption in the pharmaceutical industry. She shares her early experiences in AI, starting with her PhD research at Columbia University on image processing and natural language processing. 
At Novo Nordisk, the current focus is on applying AI to commercialization functions including – marketing, legal, and HR – beyond its traditional use in drug discovery. Alicia highlights key use cases such as generative AI for knowledge search, content generation for marketing campaigns, and traditional AI techniques for deriving insights about healthcare providers. She also emphasizes the importance of applying a product mindset to AI development by evaluating user needs, business value, and compliance from the outset.
Alicia notes that adding effective governance can help innovation move in the right direction. She also talks about an internal AI Ambassador Program and emphasizes the importance of designing intuitive AI tools to increase adoption. She concludes by discussing future trends in AI, including contextual intelligence, user-centric design, and the opportunity for AI to enhance, rather than replace human decision-making. Take a listen.]]>
                </itunes:subtitle>
                                <itunes:title>
                    <![CDATA[Aligning AI Fundamentals with User Experience in Pharma]]>
                </itunes:title>
                                                <itunes:explicit>false</itunes:explicit>
                <content:encoded>
                    <![CDATA[<a style="color:#cccccc;text-decoration:none;" title="The Big Unlock Podcast" href="https://soundcloud.com/thebigunlock" target="_blank" rel="noreferrer noopener">The Big Unlock Podcast</a> · <a style="color:#cccccc;text-decoration:none;" title="Aligning AI Fundamentals with User Experience in Pharma - Podcast with Alicia Abella" href="https://soundcloud.com/thebigunlock/aligning-ai-fundamentals-with-user-experience-in-pharma-podcast-with-alicia-abella" target="_blank" rel="noreferrer noopener">Aligning AI Fundamentals with User Experience in Pharma – Podcast with Alicia Abella</a>
<p>In this episode, Alicia Abella, AI Product Lead at Novo Nordisk, discusses how she is helping drive responsible AI adoption in the pharmaceutical industry. She shares her early experiences in AI, starting with her PhD research at Columbia University on image processing and natural language processing. </p>
<p>At Novo Nordisk, the current focus is on applying AI to commercialization functions including – marketing, legal, and HR – beyond its traditional use in drug discovery. Alicia highlights key use cases such as generative AI for knowledge search, content generation for marketing campaigns, and traditional AI techniques for deriving insights about healthcare providers. She also emphasizes the importance of applying a product mindset to AI development by evaluating user needs, business value, and compliance from the outset.</p>
<p>Alicia notes that adding effective governance can help innovation move in the right direction. She also talks about an internal AI Ambassador Program and emphasizes the importance of designing intuitive AI tools to increase adoption. She concludes by discussing future trends in AI, including contextual intelligence, user-centric design, and the opportunity for AI to enhance, rather than replace human decision-making. Take a listen.</p>]]>
                </content:encoded>
                                    <enclosure url="https://episodes.castos.com/5e2a883ca79272-39715506/2082222/c1e-8m44uoow5ou1d92g-kp92o22qcg0n-y6y2kg.mp3" length="26851464"
                        type="audio/mpeg">
                    </enclosure>
                                <itunes:summary>
                    <![CDATA[The Big Unlock Podcast · Aligning AI Fundamentals with User Experience in Pharma – Podcast with Alicia Abella
In this episode, Alicia Abella, AI Product Lead at Novo Nordisk, discusses how she is helping drive responsible AI adoption in the pharmaceutical industry. She shares her early experiences in AI, starting with her PhD research at Columbia University on image processing and natural language processing. 
At Novo Nordisk, the current focus is on applying AI to commercialization functions including – marketing, legal, and HR – beyond its traditional use in drug discovery. Alicia highlights key use cases such as generative AI for knowledge search, content generation for marketing campaigns, and traditional AI techniques for deriving insights about healthcare providers. She also emphasizes the importance of applying a product mindset to AI development by evaluating user needs, business value, and compliance from the outset.
Alicia notes that adding effective governance can help innovation move in the right direction. She also talks about an internal AI Ambassador Program and emphasizes the importance of designing intuitive AI tools to increase adoption. She concludes by discussing future trends in AI, including contextual intelligence, user-centric design, and the opportunity for AI to enhance, rather than replace human decision-making. Take a listen.]]>
                </itunes:summary>
                                    <itunes:image href="https://episodes.castos.com/5e2a883ca79272-39715506/images/2082222/c1a-gd22-347k1r1pixkm-hdbpdy.png"></itunes:image>
                                                                            <itunes:duration>00:27:59</itunes:duration>
                                                    <itunes:author>
                    <![CDATA[Rohit Mahajan &amp; Ritu M. Uberoy]]>
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